Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques (LCBPT)
CNRS UMR 8601
Université de Paris, Campus Saint-Germain-des-Prés
45 Rue des Saints Pères
75006, Paris, France

Laboratoire des Biomolécules
CNRS UMR 7203, http://www.paris-en-resonance.fr/
École Normale Supérieure, Département de Chimie
24 rue Lhomond
75005 Paris, France

Mathieu BAUDIN

Research Engineer

Laboratoire de Chimie et Biochimie pharmacologiques et toxicologiques (LCBPT) – CNRS UMR 8601
Université de Paris, Campus Saint-Germain-des-Prés
45 Rue des Saints Pères
75006, Paris, France

 Laboratoire des Biomolécules
CNRS UMR 7203, http://www.paris-en-resonance.fr/
École Normale Supérieure, Département de Chimie
24 rue Lhomond
75005 Paris, France

Biography

Mathieu Baudin, is a CNRS research engineer, sharing his position between two magnetic resonance laboratories at Université de Paris and École Normale Supérieure. He graduated in 2011 from his engineering diploma from École Centrale Marseille, and from his Master’s degree in chemistry (with a specialty in analytical chemistry) from Université Paul Cézanne Aix-Marseille III (now Aix-Marseille Université). He performed his Master’s degree thesis with Prof. Thomas Meersmann (University of Nottingham, U.K.) on hyperpolarization of noble gases via optical pumping for translational medical imaging.

He then obtained his PhD in indsutrial engineering from the École Nationale Supérieure des Arts et Métiers, after working on his thesis at CERN (European Organization for Nuclear Research) from 2011 to 2014. His topic of studies was the optimization of intervention planning and scheduling in radioactive environments. This PhD work of three years was followed by one additional year at CERN as a radiation protection physicist in particle accelerator facilities.

In September 2015, he joined back the NMR community within Prof. Geoffrey Bodenhausen’s groups, first at EPFL (Lausanne, Switzerland) and then at the École Normale Supérieure. There, he specialized in dissolution Dynamic Nuclear Polarization (D-DNP), in particular in the development of new instrumentation and methods. His expertise includes the optimization of the DNP sample and cross polarization sequences, development and operation of state of the art “cryogen-consumption-free” polarizers as well as several applications of D-DNP, among which the study of cell metabolism.

In January 2019, he was appointed as a research engineer with the CNRS (Centre National de la Recherche Scientifique). He now shares his time between two laboratories on a joint instrumental  platform dedicated to D-DNP:

Curriculum Vitae

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Teaching activities

Lectures on quantitative aspects of Nuclear Magnetic Resonance at Master level, Curriculum “Frontiers in Chemistry”, itinerary “SAFE”, Université de Paris. Supervision of interns at master level.

Research grants

2022: Young researcher grant from the French National Research Agency (ANR JCJC) – ANR-22-CE29-0003-01 PolarGlu

Publications

2023

K. Dos Santos, G. Bertho , C. Caradeuc, V. Baud, A. Montagne, D. Abergel, N. Giraud, M. Baudin, A Toolbox For Glutamine Use In Dissolution Dynamic Nuclear Polarization: From Enzymatic Reaction Monitoring To The Study Of Cellular Metabolic Pathways And Imaging. Chemphyschem. 2023 Mar 27:e202300151. doi: 10.1002/cphc.202300151. Epub ahead of print. PMID: 36973178.

2022

G. Bertho, L. Lordello, X. Chen, C. Lucas-Torres, I.-E.Oumezziane, C. Caradeuc, M. Baudin, S. Nuan-Aliman, C. Thieblemont, V. Baud, N. Giraud, Ultrahigh-Resolution NMR with Water Signal Suppression for a Deeper Understanding of the Action of Antimetabolic Drugs on Diffuse Large B-Cell Lymphoma, J. Proteome Res. 2022, 21, 4, 1041–1051, DOI: https://doi.org/10.1021/acs.jproteome.1c00914

D. Guarin, D. Carnevale, M. Baudin, P. Pelupessy, D. Abergel, G. Bodenhausen, Effects of Microwave Gating on Nuclear Spin Echoes in Dynamic Nuclear Polarization, . Phys. Chem. Lett. 2022, 13, 1, 175–182, DOI: https://doi.org/10.1021/acs.jpclett.1c03436

2021

D. Carnevale, G. Mouchaham, S. Wang, M. Baudin, C. Serre, G. Bodenhausen, and D. Abergel (2021). Natural abundance oxygen-17 solid-state NMR of metal organic frameworks enhanced by dynamic nuclear polarization. Physical Chemistry Chemical Physics, 23(3), 2245-2251.
DOI:
https://doi.org/10.1039/D0CP06064J

2020

B. Aghelnejad, S. Marhabaie, M. Baudin, G. Bodenhausen and D. Carnevale, Spin thermometry: A Straightforward Measure of Millikelvin Deuterium Spin Temperatures Achieved by Dynamic Nuclear Polarization, J. Phys. Chem. Lett 2020, 11, 9, 3219–3225, April 6 2020, DOI: https://doi.org/10.1021/acs.jpclett.0c00713

2018

M. Baudin, B. Vuichoud, A. Bornet, G. Bodenhausen and S. Jannin, A Cryogen-Consumption-Free System for Dynamic Nuclear Polarization at 9.4 T, Journal of Magnetic Resonance, Journal of Magnetic Resonance 294 (2018) 115–121, DOI: https://doi.org/10.1016/j.jmr.2018.07.001.

K. L. Ivanov, T. Kress, M. Baudin, D. Guarin, D. Abergel, G. Bodenhausen, and D. Kurzbach, Relaxation of long-lived modes in NMR of deuterated methyl groups, The Journal of Chemical Physics 149, 054202 (2018); DOI: https://doi.org/10.1063/1.5031177.

M. Cavaillès, A. Bornet, X. Jaurand, B. Vuichoud, D. Baudouin, M. Baudin, L. Veyre, G. Bodenhausen, J.-N. Dumez, S. Jannin, C. Copéret and C. Thieuleux, Tailored microstructured hyperpolarizing matrices for optimal magnetic resonance imaging, Angew. Chem. Int. Ed Engl. 57 (2018) 7453–7457.

2017

D.L. Silverio, H.A. van Kalkeren, T.-C. Ong, M. Baudin, M. Yulikov, L. Veyre, P. Berruyer, S. Chaudhari, D. Gajan, D. Baudouin, M. Cavaillès, B. Vuichoud, A. Bornet, G. Jeschke, G. Bodenhausen, A. Lesage, L. Emsley, S. Jannin, C. Thieuleux, and C. Copéret, Tailored Polarizing Hybrid Solids with Nitroxide Radicals Localized in Mesostructured Silica Walls. Helv. Chim. Acta, 100: n/a, e1700101. DOI:10.1002/hlca.201700101, May 2017.

E. Banach, C. Invernizzi, M. Baudin, R. Neier and D. Carnevale, Columnar self-assembly of N,N’,N’’-trihexylbenzene-1,3,5-tricarboxamides investigated by means of NMR spectroscopy and computational methods in solution and solid state, Phys. Chem. Chem. Phys., 2017, DOI: 10.1039/c6cp05598b.

2016

A. Bornet, A. Pinon, A. Jhajharia, M. Baudin, L. Emsley, G. Bodenhausen, J. H. Ardenkjær-Larsen and
S. Jannin
, Microwave-Gated Dynamic Nuclear Polarization, Physical Chemistry Chemical Physics,
September 2016.

Before 2016

Bonnal et al., OpenSE: a Systems Engineering Framework Particularly Suited to Particle Accelerator Studies and Development Projects, 7th IPAC Conference, Busan, Korea, May 2016.

Baudin, P. Bonnal, and J.-M. Ruiz, The Collaborative DSM: a new way to handle complex collaborative planning and scheduling processes, 16th International DSM Conference Paris, France, 2014.

Fabry, M. Baudin, B. Feral, L. Vanherpe, and L. Tabourot, Intervention Modelling at High-Energy Particle Accelerators, 5th IPAC Conference, Dresden, Germany, June 2014.

Baudin, P. Bonnal, B. Nicquevert, and J.-M. Ruiz, An Enhanced Planning and Scheduling Approach Suited to the Requirements of Collaborative Project Management, Journal of Modern Project Management., vol. 1, no. 2, 2013.

Baudin, P. Bonnal, and J.-M. Ruiz, Combining Activity DSM with Temporal Logic for Collaborative Planning and Scheduling. InTech, International Journal of Advanced Robotic Systems, Manuel Ferre, Jouni Mattila, Bruno Siciliano, Pierre Bonnal (Ed.), 2013.

Bonnal, M. Baudin, and J.M. Ruiz, Systems Engineering Issues in Scientific Facilities Subject to Ionizing Radiations, International Journal of Advanced Robotic Systems, InTech, 2013.

Bonnal, M. Baudin, and J. De Jonghe, Merging PDM, RSM and LSM scheduling approaches into a single construction project scheduling system, The Journal of Modern Project Management, vol 1, issue 2, pp6-17, 2013.

Fabry, T., Vanherpe, L., Baudin, M., Theis, C., Braesch, C., Feral, B., Interactive intervention planning in particle accelerator environments with ionizing radiation, NIMA (Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment), vol 708, April 21st 2013, pp. 32-38, 2013.

Baudin, P. Bonnal, and J. De Jonghe, A DSM Based ‘2.0’ System for Human Intervention Planning and Scheduling in Facilities Emitting Ionizing Radiations, in Gain competitive advantage by managing complexity: Proceedings of the 14th International DSM Conference, 2012.

Bonnal, M. Baudin, and J.-M. Ruiz. Handling a Design Structure Matrix based on fuzzy data. in Gain competitive advantage by managing complexity: Proceedings of the 14th International DSM Conference, 2012.

Souchay et al., The construction of the large quasar astrometric catalogue (LQAC), Astronomy and Astrophysics, Volume 494, Number 2, February 2009.

Souchay et al., The LQAC Compilation of the Quasars Catalogues, AIP Conference Proceedings. Vol. 1043. No. 1. AIP, 2008.