Recent Publications

1. Brom, J.; Maruani, A.; Micouin, L.; Benedetti, E. “Light-driven reductive cleavage of sulfonamides promoted by thiourea organophotosensitizers”. J. Org. Chem. 2023, just accepted DOI: 10.1021/acs.joc.3c00296 (Preprint ChemRxiv – DOI: 10.26434/chemrxiv-2022-jvdqw)
2. Fleurisson, C.; Graidia, N.; Foricher, Y.; Benedetti, E.; Micouin, L.;  “Intramolecular Buchwald-Hartwig N-Arylation of Bicyclic Hydrazines: Practical Access to Spiro[indoline-2,3′-piperidines]”  Org. Biomol. Chem. 2023, just accepted DOI: 10.1039/D3OB00406F (Preprint ChemRxiv – DOI: 10.26434/chemrxiv-2022-rqsqc)

1. Flavie Bouchet, Jean-Philippe Barnier, Ines Sayah, Youcef Bagdad, Maria A. Miteva, Michel Arthur, Mélanie Ethève-Quelquejeu, Laura Iannazzo “Ruthenium-Catalyzed Cycloaddition for Introducing Chemical Di-versity in Second generation b-Lactamase inhibitors”. ChemMedChem 2023, e202300077.
2. Rančić A., Babić N., Orio M., Peyrot F. “Structural Features Governing the Metabolic Stability of Tetraethyl-Substituted Nitroxides in Rat Liver Microsomes”  Antioxidants, 2023, 12(2), 402. DOI:  https://doi.org/10.3390/antiox12020402

1. Felder, S.; Delcourt, M.-L.; Rodríguez, R.; Favereau, L.; Jeanne Crassous, J.; Micouin, L.; Benedetti, E. “Compact CPL emitters based on a [2.2]paracyclophane scaffold: recent developments and future perspectives”, J. Mater. Chem. C 2023, 11, 2053 DOI: https://doi.org/10.1039/D2TC04885J
2. Galardon, E.; Mathas, N.; Padovani, D.; Le Corre, L.; Poncet, G.; Dairou, J. “Persulfidation of DJ-1: Mechanism and Consequences.” Biomolecules 2023, 13, 27. DOI: https://doi.org/10.3390/biom13010027
   

1. Chiara Figazzolo, Frédéric Bonhomme, Saidbakhrom Saidjalolov, Mélanie Ethève-Quelquejeu, Marcel Hollenstein “Enzymatic synthesis of vancomycin-modified DNA”, Molecule, 2022, doi.org/10.3390/molecules27248927

1. C. Kitoun, S. Saidjalolov, D. Bouquet, F. Djago, Q. Blancart Remaury, B. Sargueil, P. Poinot, Pauline; M. Etheve-Quelquejeu, L. Iannazzo “Traceless Staudinger Ligation to Access to Stable Aminoacyl- or Peptidyl-dinucleotides” ACS Omega., 2022, just accepted.
2. Rietmeyer, L.; Li de la Sierra-Gallay, I.; Schepers, G.; Dorchêne, D.; Iannazzo, L.; Patin, D.; Touzé, T.; van Tilbeurgh, H.; Herdewijn, P.; Etheve-Quelquejeu, M.; Fonvielle, M. “Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis” Nucleic Acids Research, 2022, just accepted
3. S. Felder, C. Sagné, E. Benedetti, L. Micouin “Small-Molecule 3D Ligand for RNA Recognition: Tuning Selectivity
   through Scaffold Hopping” ACS Chemical Biology, 2022, 17, 3069. DOI: https://doi.org/10.1021/acschembio.2c00171

1) J.-P. Barnier, S. Saidjalolov, F. Bouchet, L. Mayer, Z. Edoo, I. Sayah, L. Iannazzo, M.e Ethève-Quelquejeu, J.-L. Mainardi, E. Braud “Modulation of the Specificity of Carbapenems and Diazabicyclooctanes for Selective Activity against Mycobacterium tuberculosis” Antimicrob. Agents Chemother. 2022, Ahead of Print

DOI: https://doi.org/10.1128/aac.02357-21

1) F. Peyrot, S. Lajnef, D.-L. Versace. “Electron Paramagnetic Resonance Spin Trapping (EPR–ST) Technique in Photopolymerization Processes” Catalysts, 2022, 12, (7), 772; DOI: https://doi.org/10.3390/catal12070772

1) V. Meynier, L. Iannazzo, M. Catala, S. Oerum, E. Braud, C.Atdjian, P. Barraud, M. Fonvielle, C. Tisné, M.Ethève-Quelquejeu “Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase” Nucleic Acids Research, 2022, 50, (10), 5793–5806. DOI: https://doi.org/10.1093/nar/gkac354

1. M. F. Cunha,   I.Pranke, A. Sassi, C. Schreiweis, S.  Moriceau, D. Vidovic, A. Hatton, M. S. Carlon, G. Creste, F. Berhal, G. Prestat, R. Freund, N. Odolczyk, J. P. Jais, C. Gravier-Pelletier, P.  Zielenkiewicz, V. Jullien, A. Hinzpeter, F. Oury, A. Edelman, I. Sermet-Gaudelus “Systemic Bis-Phosphinic Acid Derivative Restores Chloride Transport in Cystic Fibrosis Mice” Sci Rep 2022, 12 (1), 6132. DOI: https://doi.org/10.1038/s41598-022-09678-9.
2. Li, K. Aubertin, D. Onidas, P. Nizard, N. Felidj, F. Gazeau, C. Mangeney, Y. Luo “Recent advances in non-plasmonic SERS nanostructures for biomedical applications” WIREs Nanomedicine & Nanobiotechnology 2022. DOI: https://doi.org/10.1002/wnan.1795

1) M. Oliver, L, Le Corre, M. Poinsot, M, Bosco, H. Wan, A. Amoroso, B. Joris, A. Bouhss, S. Calvet-Vitale, C. Gravier-Pelletier “A Sub-Micromolar MraYAA Inhibitor with an Aminoribosyl Uridine Structure and a (S,S)-Tartaric Diamide: Synthesis, Biological Evaluation and Molecular Modeling” Molecules 2022, 27(6), 1769. DOI:  https://doi.org/10.3390/molecules27061769

1. D. Padovani, E. Galardon, “Molecular Basis for the Interaction of Catalase with d-Penicillamine: Rationalization of Some of Its Deleterious Effects” Chem. Res. Toxicol. 2022, 35, 3, 412–421 DOI: https://doi.org/10.1021/acs.chemrestox.1c00313

1. D. R. Boyd, N. D. Sharma, P. J. Stevenson, P. Hoering, C. C. R. Allen, P. M. Dansette “Monooxygenase- and Dioxygenase-Catalyzed Oxidative Dearomatization of Thiophenes by Sulfoxidation, cis-Dihydroxylation and Epoxidation”. Int J Mol Sci. 2022, 23(2) 909. DOI:https://doi.org/10.3390/ijms23020909 
2. Li, P. Nizard, D. Onidas, A. Lamouri, J. Pinson, S. Mahouche-Chergui, K. Aubertin, F. Gazeau, Y. Luo, C. Mangeney “SERS Tags Derived from Silver Nanoparticles and Aryl Diazonium Salts for Cell Raman Imaging” Nanoscale 2022, 14, 1452. DOI: https://doi.org/10.1039/D1NR03148A
3. Bicyclic 5-5 systems with one ring junction nitrogen atom: Two extra heteroatoms 2:0 Benedetti, E.; Micouin, L. Reference Collection in Chemistry, Molecular Science and Chemical Engineering Wiley, 2022. Volume 11, pp 145-173. DOI:10.1016/B978-0-12-409547-2.14935-2 

1. S. Felder, M.-L. Delcourt, M.H.E. Bousquet, D.  Jacquemin, R. Rodríguez, L. Favereau, J. Crassous, L. Micouin, E. Benedetti “Planar chiral analogues of PRODAN based on a [2.2]paracyclophane scaffold: Synthesis and photophysical studies”. J. Org. Chem. 2021, just accepted
2. G. Kirby, L. Grimaud, M. R. Vitale,  G. Prestat, F. Berhal “Iron(ii)-catalyzed intermolecular aziridination of alkenes employing hydroxylamine derivatives as clean nitrene sources” Green Chem., 2021,23, 9428-9432. https://doi.org/10.1039/D1GC03495B
3. G. De Leener, D. Over, O. Reinaud, I. Jabin “Turning on anion and betaine hosting by a small structural change of a biomimetic cavity: a case study” Supramol. Chem. 2021, DOI: 10.1080/10610278.2021.2011890
   
4. Bitam, S.; Elbahnsi, A.; Creste, G.; Pranke, I.; Chevalier, B.; Berhal, F.; Hoffmann, B.; Servel, N.; Tondelier, D.; Hatton, A.; Moquereau, C.; Faria Da Cunha, M.; Pastor, A.; Lepissier, A.; Hinzpeter, A.; Mornon, J.-P.; Prestat, G.; Edelman, A.; Callebaut, I.; Gravier-Pelletier, C.; Sermet-Gaudelus, I. “New Insights into Structure and Function of Bis-Phosphinic Acid Derivatives and Implications for CFTR Modulation.” Sci Rep 2021, 11, 6842.
   DOI: https://doi.org/10.1038/s41598-021-83240-x
5. Bardin, E.; Pastor, A.; Semeraro, M.; Golec, A.; Hayes, K.; Chevalier, B.; Berhal, F.; Prestat, G.; Hinzpeter, A.; Gravier-Pelletier, C.; Pranke, I.; Sermet-Gaudelus, I. “Modulators of CFTR. Updates on Clinical Development and Future Directions.” Eur. J. Med. Chem. 2021, 113195  DOI: doi.org/10.1016/j.ejmech.2021.113195
6. Oliver, M.; Le Corre, L.; Poinsot, M.; Corio, A.; Madegard, L.; Bosco, M.; Amoroso, A.; Joris, B.; Auger, R.; Touzé, T.; Bouhss, A.; Calvet-Vitale, S.; Gravier-Pelletier, C.“Synthesis, biological evaluation and molecular modeling of urea-containing MraY inhibitors.”  Org. Biomol. Chem. 2021, 19(26), 5844-5866, DOI: 10.1039/D1OB00710F.
7. Pujol C, Legrand A, Parodi L, Boucher, J.-L.; Le Corre, L. et al. “Implication of folate deficiency in CYP2U1 loss of function.” J Exp Med. 2021; 218(11):e20210846. doi: 10.1084/jem.20210846.

1. S. Wu, L.A. Galan, M. Roux, F. Riobe, B. Le Guennic, Y. Guyot, T. Le Bahers, L. Micouin, O. Maury, E. Benedetti “Tuning the excited state properties of [2.2]paracyclophane-based antennas to ensure efficient sensitization of lanthanide ions or singlet oxygen generation” Inorg. Chem. 2021, 60, 16194−16203. DOI: https://doi.org/10.1021/acs.inorgchem.1c01986.
2. F. Bouchet, H. Atze,  M. Arthur, M. Etheve-Quelquejeu, L. Iannazzo “Traceless Staudinger ligation to introduce chemical diversity on β-lactamase inhibitors of second generation” Org. Lett., 2021, just accepted. 
3. Médard, X. Sun, J. Pinson, D. Li, C. Mangeney, J.-P. Michel “Electrografting and Langmuir-Blodgett: Covalently Bound Nanometer Thick Ordered Films on Graphite” Langmuir 2021, 37, 12539. DOI: https://doi.org/10.1021/acs.langmuir.1c01723

1. ​J. Haubrich, J. Font, R. B. Quast, A. Goupil-Lamy, P. Scholler, D. Nevoltris, F.Acher, P. Chames, P. Rondard, L. Prezeau, J.-P. Pin “A nanobody activating metabotropic glutamate receptor 4 discriminates between homo and heterodimers.” Proc. Natl. Acad. Sci. U S A 2021,  118 (33) e2105848118. DOI: https://doi.org/10.1073/pnas.2105848118
2. E. Brunetti, L. Marcelis, F. E. Zhurkin, M. Luhmer, I. Jabin, O. Reinaud, K. Bartik “A Water Molecule Triggers Guest Exchange at a Mono-zinc Centre Confined in a Biomimetic Calixarene Pocket: a Model for Understanding Ligand Stability in Zn Proteins” Chem. Eur. J. 2021, 27, 13730-13738 DOI:  https://doi.org/10.1002/chem.202102184.
3. Li, Y. Luo, D. Onidas, L. He, M. Jin, F. Gazeau, J. Pinson, C. Mangeney “Surface functionalization of nanomaterials by aryl diazonium salts for biomedical sciences” Adv. Colloid & Interface Science 2021, 294, 102479. DOI: https://doi.org/10.1016/j.cis.2021.102479

1. Xiao, J. Gateau, A. Brun, X. Shi, F. Gazeau, C. Mangeney, Y. Luo “Hybrid nano- and microgels doped with photoacoustic contrast agents for cancer theranostics” View 2021, 2:20200176. DOI: https://doi.org/10.1002/VIW.20200176

1. S. Felder, S. Wu, J. Brom, L. Micouin, E. Benedetti “Enantiopure planar chiral [2.2]paracyclophanes: Synthesis and applications in asymmetric organocatalysis”  Chirality, 2021, 33, 506-527 DOI: https://doi.org/10.1002/chir.23335

1. Kherbouche, D. McRae, T. Geronimi, F. Lagugné-Labarthet, A. Lamouri, A. Chevillot-Biraud, C. Mangeney, N. Felidj “Extending nanoscale patterning with multipolar surface plasmon resonances” Nanoscale 2021, 13, 11051. DOI: https://doi.org/10.1039/D1NR02181H

1. S. Felder, L. Micouin, E. Benedetti “Para‐functionalization of N‐substituted 4‐amino[2.2]paracyclophanes by regioselective formylation” Eur. J. Org. Chem., 2021, 4015-4018. DOI: https://doi.org/10.1002/ejoc.202100288
2. Barosi, A. Berisha, C. Mangeney, J. Pinson, H. Dhimane, P. I. Dalko “Efficient construction of redox responsive thin polymer layer on carbon and gold for voltage-gated delivery applications” Materials Adv. 2021, 2, 2358. DOI: https://doi.org/10.1039/D1MA00022E

1. D.A.B. Therien, D. M. McRae, C. Mangeney, N. Félidj, F. Lagugné-Labarthet “Three-Color Plasmon-Mediated Reduction of Diazonium Salts over Metasurfaces” Nanoscale Adv. 2021, 3, 2501. DOI: https://doi.org/10.1039/D0NA00862A

1. Rietmeyer, N. Fix-boulier, C. Le Fournis, L. Iannazzo, C. Kitoun, D. Patin, D. Mengin-lecreulx, M. Etheve-Quelquejeu, M. Arthur, M. Fonvielle “Partition of tRNAGly isoacceptors between protein and cell-wall peptidoglycan synthesis in Staphylococcus aureus”, Nucleic Acid Res. 2021, Accepted. DOI: http://doi.org/10.1093/nar/gkaa1242
2. S. Saidjalolov, Z. Edoo, M. Fonvielle, L. Mayer, L. Iannazzo, M. Arthur, M. Etheve-Quelquejeu, E. Braud “Synthesis of carbapenems containing peptidoglycan-mimetics and inhibition of the cross-linking activity of a transpeptidase of the L,D specificity” Chem. Eur. J., 2021, Accepted. DOI: http://doi.org/10.1002/chem.202004831
3. de Sa Nogueira D, Bourdy R, Filliol D, Quessada C, McCort-Tranchepain I, Acher F, Zwiller J, Romieu P, Befort K. “LSP2-9166, an orthosteric mGlu4 and mGlu7 receptor agonist, reduces cocaine self-administration under a progressive ratio schedule in rats” Neurosci Lett. 2020, 135603 https://doi.org/10.1016/j.neulet.2020.135603
4. K. Abbas, N. Babić, F. Peyrot. “Detection of superoxide radical in adherent living cells by electron paramagnetic resonance (EPR) spectroscopy using cyclic nitrones”. Methods Mol. Biol. 2021, 2202, 149-163. DOI: https://doi.org/10.1007/978-1-0716-0896-8_13

1. B. Li, Y. Li, C. Tomkiewicz-Raulet, P. Dao, D. Lietha, E. Yen-Pon, Z. Du, X. Coumoul, C. Garbay, M. Etheve-Quelquejeu, H. Chen “Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma” J. Med. Chem. 2020, 63, 12707-12724. DOI: 10.1021/acs.jmedchem.0c01059
2. M. Bosco, S.-J. Paik, P. Busca, S. E. H. Moore, C. Gravier-Pelletier “Synthetic Route to Glycosyl β-1C-(phosphino)-phosphonates as Unprecedented Stable Glycosyl Diphosphate Analogs and Their Preliminary Biological Evaluation” Molecules 2020, 25, 4969. DOI: 10.3390/molecules25214969
3. C. Fleurisson, E. Benedetti, L. Micouin Cyclic cis-1,3-Diamines Derived from Bicyclic Hydrazines: Synthesis and Applications Synlett 2021, 31, 858-874. DOI: 10.1055/s-0040-1707324
4. X. Chen, P. Coric, V. Larue, S. Turcaud, X. Wang, S. Nonin-Lecomte, S. Bouaziz “The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag” Eur. J. Med. Chem., 2020, 204, 112634 DOI: https://doi.org/10.1016/j.ejmech.2020.112634

1. C. Kitoun, M. Fonvielle, N. Sakkas, M. Lefresne, F. Djago, Q. Blancart Remaury, P. Poinot, M. Arthur, M. Etheve-Quelquejeu, L. Iannazzo. “Phosphine-Mediated Bioconjugation of the 3′-end of RNA” Org. Lett., 2020, Just Acccepted.   https://doi.org/10.1021/acs.orglett.0c02982
2. C. Aubry, P. Clerici, C. Gerbaud, L. Micouin, J.-L. Pernodet, S. Lautru, Revised structure of Anthelvencine A and characterization of the Anthelvencin Biosynthetic gene cluster.  ACS Chem Biol. 2020, 15, 945-951. https://doi.org/10.1021/acschembio.9b00960
3. T. Zhang, L. Le Corre, O. Reinaud, B. Colasson “A Promising Approach for Controlling the 2nd Coordination Sphere of Biomimetic Metal Complexes: Encapsulation in a Dynamic Hydrogen-Bonded Capsule” Chem. Eur. J. 2020 in press. https://doi.org/10.1002/chem.202004370.
4. J. K. Aw, K. C. Boellaard, T. K. Tan, J. Yap, Y.P. Loh, B. Colasson, È. Blanc, Y. Lam, F. M. Fung “Interacting with Three-Dimensional Molecular Structures Using an Augmented Reality Mobile App” J. Chem. Ed. 2020, 97, 3877-3881. https://doi.org/10.1021/acs.jchemed.0c00387

2) H.Liu, Ping Yi, W. Zhao, Y. Wu, F. Acher, J.-P. Pin, J. Liu and P. Rondard “Illuminating the allosteric modulation of the calcium-sensing receptor” Proc Natl Acad Sci U S A 2020, 117, 21711-21722. https://doi.org/10.1073/pnas.1922231117

3) C. Atdjian, D. Coelho, L. Iannazzo , M. Ethève-Quelquejeu, E. Braud “Synthesis of Triazole-Linked SAM-Adenosine Conjugates: Functionalization of Adenosine at N-1 or N-6 Position without Protecting Groups” Molecules 2020, 25, 3241; https://doi.org/10.3390/molecules25143241

1. N. Babić, M. Orio, F. Peyrot. “Unexpected rapid aerobic transformation of 2,2,6,6-tetraethyl-4-oxo(piperidin-1-yloxyl) radical by cytochrome P450 in the presence of NADPH: Evidence against a simple reduction of the nitroxide moiety to the hydroxylamine”. Free Radic. Biol. Med. 2020, 156, 144-156. DOI: https://doi.org/10.1016/j.freeradbiomed.2020.05.021
2. Kherbouche, Y. Luo, N. Félidj, C. Mangeney “Plasmon-Mediated Surface Functionalization: New Horizons for the Control of Surface Chemistry on the Nanoscale” Chem. Mater. 2020, 32, 5442. DOI: https://doi.org/10.1021/acs.chemmater.0c00921

1. Y. Luo, Y. Xiao, D. Onidas, L. Iannazzo, M. Ethève-Quelquejeu, A. Lamouri, N. Félidj, S. Mahouche-Chergui, T. Brulé, N. Gagey-Eilstein, F. Gazeau, C. Mangeney “Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles”.  Chem. Commun., 2020, Advance Article https://doi.org/10.1039/D0CC02842H
2. Decorbie, I. Tijunelyte, S. Gam-Derouich, J. Solard, A. Lamouri, P. Decorse, N. Felidj, C. Gauchotte-Lindsay, E. Rinnert, C. Mangeney, N. Lidgi-Guigui “Sensing Polymer/Paracetamol Interaction with an Independent Component Analysis-Based SERS-MIP Nanosensor” Plasmonics 2020, 15, 1533. DOI: https://doi.org/10.1007/s11468-020-01177-9
3. Luo, Y. Xiao, D. Onidas, L. Iannazzo, M. Ethève-Quelquejeu, A. Lamouri, N. Félidj, S. Mahouche-Chergui, T. Brulé, N. Gagey-Eilstein, F. Gazeau, C. Mangeney “Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles” Chem. Commun. 2020, 56, 6822. DOI: https://doi.org/10.1039/D0CC02842H

(2) Poirel O, Mamer LE, Herman MA, Arnulf-Kempcke M, Kervern M, Potier B, Miot S, Wang J, Favre-Besse FC, Brabet I, Laras Y, Bertrand HO, Acher F, Pin JP, Puel JL, Giros B, Epelbaum J, Rosenmund C, Dutar P, Daumas S, El Mestikawy S, Pietrancosta N. “LSP5-2157 a new inhibitor of vesicular glutamate transporters.” Neuropharmacology. 2020 164 107902. doi: 10.1016/j.neuropharm.2019.107902.

1. Médard, P. Decorse, C. Mangeney, J. Pinson, M. Fagnoni, S. Protti “Simultaneous Photografting of Two Organic Groups on a Gold Surface by using Arylazo Sulfones as Single Precursors” Langmuir 2020, 36, 11, 2786. DOI: https://doi.org/10.1021/acs.langmuir.9b03878

1. H. Habrian, J. Levitz, V. Vyklicky, Z. Fu, A.Hoagland, I. McCort-Tranchepain, F. Acher, E. Y. Isacoff “Conformational pathway provides unique sensitivity to a synaptic mGluR” Nature Commun. 2019, 10, 5572 doi:10.1038/s41467-019-13407-8
2. Abi Fayssal, A. Giungi, F. Berhal, G. Prestat “Iron-Catalyzed Intra-intermolecular Aminoazidation of Alkenes” Org. Process Res. Dev., 10.1021/acs.oprd.9b00400

N. Babić, F. Peyrot. “New synthetic route to 2,2,6,6-tetraethylpiperidin-4-one: A key-intermediate towards tetraethyl nitroxides”. Tet. Lett. 2019, 60(44), 151207. DOI: https://doi.org/10.1016/j.tetlet.2019.151207

N. Babić, F. Peyrot. “Molecular Probes for Evaluation of Oxidative Stress by In Vivo EPR Spectroscopy and Imaging: State-of-the-Art and Limitations”. Magnetochemistry 2019, I(1), 13. DOI: https://doi.org/10.3390/magnetochemistry5010013

1. Brom, J.; Maruani, A.; Micouin, L.; Benedetti, E. “Light-driven reductive cleavage of sulfonamides promoted by thiourea organophotosensitizers”. J. Org. Chem. 2023, just accepted DOI: 10.1021/acs.joc.3c00296 (Preprint ChemRxiv – DOI: 10.26434/chemrxiv-2022-jvdqw)
2. Fleurisson, C.; Graidia, N.; Foricher, Y.; Benedetti, E.; Micouin, L.;  “Intramolecular Buchwald-Hartwig N-Arylation of Bicyclic Hydrazines: Practical Access to Spiro[indoline-2,3′-piperidines]”  Org. Biomol. Chem. 2023, just accepted DOI: 10.1039/D3OB00406F (Preprint ChemRxiv – DOI: 10.26434/chemrxiv-2022-rqsqc)

1. Flavie Bouchet, Jean-Philippe Barnier, Ines Sayah, Youcef Bagdad, Maria A. Miteva, Michel Arthur, Mélanie Ethève-Quelquejeu, Laura Iannazzo “Ruthenium-Catalyzed Cycloaddition for Introducing Chemical Di-versity in Second generation b-Lactamase inhibitors”. ChemMedChem 2023, e202300077.
2. Rančić A., Babić N., Orio M., Peyrot F. “Structural Features Governing the Metabolic Stability of Tetraethyl-Substituted Nitroxides in Rat Liver Microsomes”  Antioxidants, 2023, 12(2), 402. DOI:  https://doi.org/10.3390/antiox12020402

1. Felder, S.; Delcourt, M.-L.; Rodríguez, R.; Favereau, L.; Jeanne Crassous, J.; Micouin, L.; Benedetti, E. “Compact CPL emitters based on a [2.2]paracyclophane scaffold: recent developments and future perspectives”, J. Mater. Chem. C 2023, 11, 2053 DOI: https://doi.org/10.1039/D2TC04885J
2. Galardon, E.; Mathas, N.; Padovani, D.; Le Corre, L.; Poncet, G.; Dairou, J. “Persulfidation of DJ-1: Mechanism and Consequences.” Biomolecules 2023, 13, 27. DOI: https://doi.org/10.3390/biom13010027
   

1. Chiara Figazzolo, Frédéric Bonhomme, Saidbakhrom Saidjalolov, Mélanie Ethève-Quelquejeu, Marcel Hollenstein “Enzymatic synthesis of vancomycin-modified DNA”, Molecule, 2022, doi.org/10.3390/molecules27248927

1. C. Kitoun, S. Saidjalolov, D. Bouquet, F. Djago, Q. Blancart Remaury, B. Sargueil, P. Poinot, Pauline; M. Etheve-Quelquejeu, L. Iannazzo “Traceless Staudinger Ligation to Access to Stable Aminoacyl- or Peptidyl-dinucleotides” ACS Omega., 2022, just accepted.
2. Rietmeyer, L.; Li de la Sierra-Gallay, I.; Schepers, G.; Dorchêne, D.; Iannazzo, L.; Patin, D.; Touzé, T.; van Tilbeurgh, H.; Herdewijn, P.; Etheve-Quelquejeu, M.; Fonvielle, M. “Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis” Nucleic Acids Research, 2022, just accepted
3. S. Felder, C. Sagné, E. Benedetti, L. Micouin “Small-Molecule 3D Ligand for RNA Recognition: Tuning Selectivity
   through Scaffold Hopping” ACS Chemical Biology, 2022, 17, 3069. DOI: https://doi.org/10.1021/acschembio.2c00171

1) J.-P. Barnier, S. Saidjalolov, F. Bouchet, L. Mayer, Z. Edoo, I. Sayah, L. Iannazzo, M.e Ethève-Quelquejeu, J.-L. Mainardi, E. Braud “Modulation of the Specificity of Carbapenems and Diazabicyclooctanes for Selective Activity against Mycobacterium tuberculosis” Antimicrob. Agents Chemother. 2022, Ahead of Print

DOI: https://doi.org/10.1128/aac.02357-21

1) F. Peyrot, S. Lajnef, D.-L. Versace. “Electron Paramagnetic Resonance Spin Trapping (EPR–ST) Technique in Photopolymerization Processes” Catalysts, 2022, 12, (7), 772; DOI: https://doi.org/10.3390/catal12070772

1) V. Meynier, L. Iannazzo, M. Catala, S. Oerum, E. Braud, C.Atdjian, P. Barraud, M. Fonvielle, C. Tisné, M.Ethève-Quelquejeu “Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase” Nucleic Acids Research, 2022, 50, (10), 5793–5806. DOI: https://doi.org/10.1093/nar/gkac354

1. M. F. Cunha,   I.Pranke, A. Sassi, C. Schreiweis, S.  Moriceau, D. Vidovic, A. Hatton, M. S. Carlon, G. Creste, F. Berhal, G. Prestat, R. Freund, N. Odolczyk, J. P. Jais, C. Gravier-Pelletier, P.  Zielenkiewicz, V. Jullien, A. Hinzpeter, F. Oury, A. Edelman, I. Sermet-Gaudelus “Systemic Bis-Phosphinic Acid Derivative Restores Chloride Transport in Cystic Fibrosis Mice” Sci Rep 2022, 12 (1), 6132. DOI: https://doi.org/10.1038/s41598-022-09678-9.
2. Li, K. Aubertin, D. Onidas, P. Nizard, N. Felidj, F. Gazeau, C. Mangeney, Y. Luo “Recent advances in non-plasmonic SERS nanostructures for biomedical applications” WIREs Nanomedicine & Nanobiotechnology 2022. DOI: https://doi.org/10.1002/wnan.1795

1) M. Oliver, L, Le Corre, M. Poinsot, M, Bosco, H. Wan, A. Amoroso, B. Joris, A. Bouhss, S. Calvet-Vitale, C. Gravier-Pelletier “A Sub-Micromolar MraYAA Inhibitor with an Aminoribosyl Uridine Structure and a (S,S)-Tartaric Diamide: Synthesis, Biological Evaluation and Molecular Modeling” Molecules 2022, 27(6), 1769. DOI:  https://doi.org/10.3390/molecules27061769

1. D. Padovani, E. Galardon, “Molecular Basis for the Interaction of Catalase with d-Penicillamine: Rationalization of Some of Its Deleterious Effects” Chem. Res. Toxicol. 2022, 35, 3, 412–421 DOI: https://doi.org/10.1021/acs.chemrestox.1c00313

1. D. R. Boyd, N. D. Sharma, P. J. Stevenson, P. Hoering, C. C. R. Allen, P. M. Dansette “Monooxygenase- and Dioxygenase-Catalyzed Oxidative Dearomatization of Thiophenes by Sulfoxidation, cis-Dihydroxylation and Epoxidation”. Int J Mol Sci. 2022, 23(2) 909. DOI:https://doi.org/10.3390/ijms23020909 
2. Li, P. Nizard, D. Onidas, A. Lamouri, J. Pinson, S. Mahouche-Chergui, K. Aubertin, F. Gazeau, Y. Luo, C. Mangeney “SERS Tags Derived from Silver Nanoparticles and Aryl Diazonium Salts for Cell Raman Imaging” Nanoscale 2022, 14, 1452. DOI: https://doi.org/10.1039/D1NR03148A
3. Bicyclic 5-5 systems with one ring junction nitrogen atom: Two extra heteroatoms 2:0 Benedetti, E.; Micouin, L. Reference Collection in Chemistry, Molecular Science and Chemical Engineering Wiley, 2022. Volume 11, pp 145-173. DOI:10.1016/B978-0-12-409547-2.14935-2 

1. S. Felder, M.-L. Delcourt, M.H.E. Bousquet, D.  Jacquemin, R. Rodríguez, L. Favereau, J. Crassous, L. Micouin, E. Benedetti “Planar chiral analogues of PRODAN based on a [2.2]paracyclophane scaffold: Synthesis and photophysical studies”. J. Org. Chem. 2021, just accepted
2. G. Kirby, L. Grimaud, M. R. Vitale,  G. Prestat, F. Berhal “Iron(ii)-catalyzed intermolecular aziridination of alkenes employing hydroxylamine derivatives as clean nitrene sources” Green Chem., 2021,23, 9428-9432. https://doi.org/10.1039/D1GC03495B
3. G. De Leener, D. Over, O. Reinaud, I. Jabin “Turning on anion and betaine hosting by a small structural change of a biomimetic cavity: a case study” Supramol. Chem. 2021, DOI: 10.1080/10610278.2021.2011890
   
4. Bitam, S.; Elbahnsi, A.; Creste, G.; Pranke, I.; Chevalier, B.; Berhal, F.; Hoffmann, B.; Servel, N.; Tondelier, D.; Hatton, A.; Moquereau, C.; Faria Da Cunha, M.; Pastor, A.; Lepissier, A.; Hinzpeter, A.; Mornon, J.-P.; Prestat, G.; Edelman, A.; Callebaut, I.; Gravier-Pelletier, C.; Sermet-Gaudelus, I. “New Insights into Structure and Function of Bis-Phosphinic Acid Derivatives and Implications for CFTR Modulation.” Sci Rep 2021, 11, 6842.
   DOI: https://doi.org/10.1038/s41598-021-83240-x
5. Bardin, E.; Pastor, A.; Semeraro, M.; Golec, A.; Hayes, K.; Chevalier, B.; Berhal, F.; Prestat, G.; Hinzpeter, A.; Gravier-Pelletier, C.; Pranke, I.; Sermet-Gaudelus, I. “Modulators of CFTR. Updates on Clinical Development and Future Directions.” Eur. J. Med. Chem. 2021, 113195  DOI: doi.org/10.1016/j.ejmech.2021.113195
6. Oliver, M.; Le Corre, L.; Poinsot, M.; Corio, A.; Madegard, L.; Bosco, M.; Amoroso, A.; Joris, B.; Auger, R.; Touzé, T.; Bouhss, A.; Calvet-Vitale, S.; Gravier-Pelletier, C.“Synthesis, biological evaluation and molecular modeling of urea-containing MraY inhibitors.”  Org. Biomol. Chem. 2021, 19(26), 5844-5866, DOI: 10.1039/D1OB00710F.
7. Pujol C, Legrand A, Parodi L, Boucher, J.-L.; Le Corre, L. et al. “Implication of folate deficiency in CYP2U1 loss of function.” J Exp Med. 2021; 218(11):e20210846. doi: 10.1084/jem.20210846.

1. S. Wu, L.A. Galan, M. Roux, F. Riobe, B. Le Guennic, Y. Guyot, T. Le Bahers, L. Micouin, O. Maury, E. Benedetti “Tuning the excited state properties of [2.2]paracyclophane-based antennas to ensure efficient sensitization of lanthanide ions or singlet oxygen generation” Inorg. Chem. 2021, 60, 16194−16203. DOI: https://doi.org/10.1021/acs.inorgchem.1c01986.
2. F. Bouchet, H. Atze,  M. Arthur, M. Etheve-Quelquejeu, L. Iannazzo “Traceless Staudinger ligation to introduce chemical diversity on β-lactamase inhibitors of second generation” Org. Lett., 2021, just accepted. 
3. Médard, X. Sun, J. Pinson, D. Li, C. Mangeney, J.-P. Michel “Electrografting and Langmuir-Blodgett: Covalently Bound Nanometer Thick Ordered Films on Graphite” Langmuir 2021, 37, 12539. DOI: https://doi.org/10.1021/acs.langmuir.1c01723

1. ​J. Haubrich, J. Font, R. B. Quast, A. Goupil-Lamy, P. Scholler, D. Nevoltris, F.Acher, P. Chames, P. Rondard, L. Prezeau, J.-P. Pin “A nanobody activating metabotropic glutamate receptor 4 discriminates between homo and heterodimers.” Proc. Natl. Acad. Sci. U S A 2021,  118 (33) e2105848118. DOI: https://doi.org/10.1073/pnas.2105848118
2. E. Brunetti, L. Marcelis, F. E. Zhurkin, M. Luhmer, I. Jabin, O. Reinaud, K. Bartik “A Water Molecule Triggers Guest Exchange at a Mono-zinc Centre Confined in a Biomimetic Calixarene Pocket: a Model for Understanding Ligand Stability in Zn Proteins” Chem. Eur. J. 2021, 27, 13730-13738 DOI:  https://doi.org/10.1002/chem.202102184.
3. Li, Y. Luo, D. Onidas, L. He, M. Jin, F. Gazeau, J. Pinson, C. Mangeney “Surface functionalization of nanomaterials by aryl diazonium salts for biomedical sciences” Adv. Colloid & Interface Science 2021, 294, 102479. DOI: https://doi.org/10.1016/j.cis.2021.102479

1. Xiao, J. Gateau, A. Brun, X. Shi, F. Gazeau, C. Mangeney, Y. Luo “Hybrid nano- and microgels doped with photoacoustic contrast agents for cancer theranostics” View 2021, 2:20200176. DOI: https://doi.org/10.1002/VIW.20200176

1. S. Felder, S. Wu, J. Brom, L. Micouin, E. Benedetti “Enantiopure planar chiral [2.2]paracyclophanes: Synthesis and applications in asymmetric organocatalysis”  Chirality, 2021, 33, 506-527 DOI: https://doi.org/10.1002/chir.23335

1. Kherbouche, D. McRae, T. Geronimi, F. Lagugné-Labarthet, A. Lamouri, A. Chevillot-Biraud, C. Mangeney, N. Felidj “Extending nanoscale patterning with multipolar surface plasmon resonances” Nanoscale 2021, 13, 11051. DOI: https://doi.org/10.1039/D1NR02181H

1. S. Felder, L. Micouin, E. Benedetti “Para‐functionalization of N‐substituted 4‐amino[2.2]paracyclophanes by regioselective formylation” Eur. J. Org. Chem., 2021, 4015-4018. DOI: https://doi.org/10.1002/ejoc.202100288
2. Barosi, A. Berisha, C. Mangeney, J. Pinson, H. Dhimane, P. I. Dalko “Efficient construction of redox responsive thin polymer layer on carbon and gold for voltage-gated delivery applications” Materials Adv. 2021, 2, 2358. DOI: https://doi.org/10.1039/D1MA00022E

1. D.A.B. Therien, D. M. McRae, C. Mangeney, N. Félidj, F. Lagugné-Labarthet “Three-Color Plasmon-Mediated Reduction of Diazonium Salts over Metasurfaces” Nanoscale Adv. 2021, 3, 2501. DOI: https://doi.org/10.1039/D0NA00862A

1. Rietmeyer, N. Fix-boulier, C. Le Fournis, L. Iannazzo, C. Kitoun, D. Patin, D. Mengin-lecreulx, M. Etheve-Quelquejeu, M. Arthur, M. Fonvielle “Partition of tRNAGly isoacceptors between protein and cell-wall peptidoglycan synthesis in Staphylococcus aureus”, Nucleic Acid Res. 2021, Accepted. DOI: http://doi.org/10.1093/nar/gkaa1242
2. S. Saidjalolov, Z. Edoo, M. Fonvielle, L. Mayer, L. Iannazzo, M. Arthur, M. Etheve-Quelquejeu, E. Braud “Synthesis of carbapenems containing peptidoglycan-mimetics and inhibition of the cross-linking activity of a transpeptidase of the L,D specificity” Chem. Eur. J., 2021, Accepted. DOI: http://doi.org/10.1002/chem.202004831
3. de Sa Nogueira D, Bourdy R, Filliol D, Quessada C, McCort-Tranchepain I, Acher F, Zwiller J, Romieu P, Befort K. “LSP2-9166, an orthosteric mGlu4 and mGlu7 receptor agonist, reduces cocaine self-administration under a progressive ratio schedule in rats” Neurosci Lett. 2020, 135603 https://doi.org/10.1016/j.neulet.2020.135603
4. K. Abbas, N. Babić, F. Peyrot. “Detection of superoxide radical in adherent living cells by electron paramagnetic resonance (EPR) spectroscopy using cyclic nitrones”. Methods Mol. Biol. 2021, 2202, 149-163. DOI: https://doi.org/10.1007/978-1-0716-0896-8_13

1. B. Li, Y. Li, C. Tomkiewicz-Raulet, P. Dao, D. Lietha, E. Yen-Pon, Z. Du, X. Coumoul, C. Garbay, M. Etheve-Quelquejeu, H. Chen “Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma” J. Med. Chem. 2020, 63, 12707-12724. DOI: 10.1021/acs.jmedchem.0c01059
2. M. Bosco, S.-J. Paik, P. Busca, S. E. H. Moore, C. Gravier-Pelletier “Synthetic Route to Glycosyl β-1C-(phosphino)-phosphonates as Unprecedented Stable Glycosyl Diphosphate Analogs and Their Preliminary Biological Evaluation” Molecules 2020, 25, 4969. DOI: 10.3390/molecules25214969
3. C. Fleurisson, E. Benedetti, L. Micouin Cyclic cis-1,3-Diamines Derived from Bicyclic Hydrazines: Synthesis and Applications Synlett 2021, 31, 858-874. DOI: 10.1055/s-0040-1707324
4. X. Chen, P. Coric, V. Larue, S. Turcaud, X. Wang, S. Nonin-Lecomte, S. Bouaziz “The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag” Eur. J. Med. Chem., 2020, 204, 112634 DOI: https://doi.org/10.1016/j.ejmech.2020.112634

1. C. Kitoun, M. Fonvielle, N. Sakkas, M. Lefresne, F. Djago, Q. Blancart Remaury, P. Poinot, M. Arthur, M. Etheve-Quelquejeu, L. Iannazzo. “Phosphine-Mediated Bioconjugation of the 3′-end of RNA” Org. Lett., 2020, Just Acccepted.   https://doi.org/10.1021/acs.orglett.0c02982
2. C. Aubry, P. Clerici, C. Gerbaud, L. Micouin, J.-L. Pernodet, S. Lautru, Revised structure of Anthelvencine A and characterization of the Anthelvencin Biosynthetic gene cluster.  ACS Chem Biol. 2020, 15, 945-951. https://doi.org/10.1021/acschembio.9b00960
3. T. Zhang, L. Le Corre, O. Reinaud, B. Colasson “A Promising Approach for Controlling the 2nd Coordination Sphere of Biomimetic Metal Complexes: Encapsulation in a Dynamic Hydrogen-Bonded Capsule” Chem. Eur. J. 2020 in press. https://doi.org/10.1002/chem.202004370.
4. J. K. Aw, K. C. Boellaard, T. K. Tan, J. Yap, Y.P. Loh, B. Colasson, È. Blanc, Y. Lam, F. M. Fung “Interacting with Three-Dimensional Molecular Structures Using an Augmented Reality Mobile App” J. Chem. Ed. 2020, 97, 3877-3881. https://doi.org/10.1021/acs.jchemed.0c00387

2) H.Liu, Ping Yi, W. Zhao, Y. Wu, F. Acher, J.-P. Pin, J. Liu and P. Rondard “Illuminating the allosteric modulation of the calcium-sensing receptor” Proc Natl Acad Sci U S A 2020, 117, 21711-21722. https://doi.org/10.1073/pnas.1922231117

3) C. Atdjian, D. Coelho, L. Iannazzo , M. Ethève-Quelquejeu, E. Braud “Synthesis of Triazole-Linked SAM-Adenosine Conjugates: Functionalization of Adenosine at N-1 or N-6 Position without Protecting Groups” Molecules 2020, 25, 3241; https://doi.org/10.3390/molecules25143241

1. N. Babić, M. Orio, F. Peyrot. “Unexpected rapid aerobic transformation of 2,2,6,6-tetraethyl-4-oxo(piperidin-1-yloxyl) radical by cytochrome P450 in the presence of NADPH: Evidence against a simple reduction of the nitroxide moiety to the hydroxylamine”. Free Radic. Biol. Med. 2020, 156, 144-156. DOI: https://doi.org/10.1016/j.freeradbiomed.2020.05.021
2. Kherbouche, Y. Luo, N. Félidj, C. Mangeney “Plasmon-Mediated Surface Functionalization: New Horizons for the Control of Surface Chemistry on the Nanoscale” Chem. Mater. 2020, 32, 5442. DOI: https://doi.org/10.1021/acs.chemmater.0c00921

1. Y. Luo, Y. Xiao, D. Onidas, L. Iannazzo, M. Ethève-Quelquejeu, A. Lamouri, N. Félidj, S. Mahouche-Chergui, T. Brulé, N. Gagey-Eilstein, F. Gazeau, C. Mangeney “Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles”.  Chem. Commun., 2020, Advance Article https://doi.org/10.1039/D0CC02842H
2. Decorbie, I. Tijunelyte, S. Gam-Derouich, J. Solard, A. Lamouri, P. Decorse, N. Felidj, C. Gauchotte-Lindsay, E. Rinnert, C. Mangeney, N. Lidgi-Guigui “Sensing Polymer/Paracetamol Interaction with an Independent Component Analysis-Based SERS-MIP Nanosensor” Plasmonics 2020, 15, 1533. DOI: https://doi.org/10.1007/s11468-020-01177-9
3. Luo, Y. Xiao, D. Onidas, L. Iannazzo, M. Ethève-Quelquejeu, A. Lamouri, N. Félidj, S. Mahouche-Chergui, T. Brulé, N. Gagey-Eilstein, F. Gazeau, C. Mangeney “Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles” Chem. Commun. 2020, 56, 6822. DOI: https://doi.org/10.1039/D0CC02842H

(2) Poirel O, Mamer LE, Herman MA, Arnulf-Kempcke M, Kervern M, Potier B, Miot S, Wang J, Favre-Besse FC, Brabet I, Laras Y, Bertrand HO, Acher F, Pin JP, Puel JL, Giros B, Epelbaum J, Rosenmund C, Dutar P, Daumas S, El Mestikawy S, Pietrancosta N. “LSP5-2157 a new inhibitor of vesicular glutamate transporters.” Neuropharmacology. 2020 164 107902. doi: 10.1016/j.neuropharm.2019.107902.

1. Médard, P. Decorse, C. Mangeney, J. Pinson, M. Fagnoni, S. Protti “Simultaneous Photografting of Two Organic Groups on a Gold Surface by using Arylazo Sulfones as Single Precursors” Langmuir 2020, 36, 11, 2786. DOI: https://doi.org/10.1021/acs.langmuir.9b03878

1. H. Habrian, J. Levitz, V. Vyklicky, Z. Fu, A.Hoagland, I. McCort-Tranchepain, F. Acher, E. Y. Isacoff “Conformational pathway provides unique sensitivity to a synaptic mGluR” Nature Commun. 2019, 10, 5572 doi:10.1038/s41467-019-13407-8
2. Abi Fayssal, A. Giungi, F. Berhal, G. Prestat “Iron-Catalyzed Intra-intermolecular Aminoazidation of Alkenes” Org. Process Res. Dev., 10.1021/acs.oprd.9b00400

N. Babić, F. Peyrot. “New synthetic route to 2,2,6,6-tetraethylpiperidin-4-one: A key-intermediate towards tetraethyl nitroxides”. Tet. Lett. 2019, 60(44), 151207. DOI: https://doi.org/10.1016/j.tetlet.2019.151207

N. Babić, F. Peyrot. “Molecular Probes for Evaluation of Oxidative Stress by In Vivo EPR Spectroscopy and Imaging: State-of-the-Art and Limitations”. Magnetochemistry 2019, I(1), 13. DOI: https://doi.org/10.3390/magnetochemistry5010013

1. Brom, J.; Maruani, A.; Micouin, L.; Benedetti, E. “Light-driven reductive cleavage of sulfonamides promoted by thiourea organophotosensitizers”. J. Org. Chem. 2023, just accepted DOI: 10.1021/acs.joc.3c00296 (Preprint ChemRxiv – DOI: 10.26434/chemrxiv-2022-jvdqw)
2. Fleurisson, C.; Graidia, N.; Foricher, Y.; Benedetti, E.; Micouin, L.;  “Intramolecular Buchwald-Hartwig N-Arylation of Bicyclic Hydrazines: Practical Access to Spiro[indoline-2,3′-piperidines]”  Org. Biomol. Chem. 2023, just accepted DOI: 10.1039/D3OB00406F (Preprint ChemRxiv – DOI: 10.26434/chemrxiv-2022-rqsqc)

1. Flavie Bouchet, Jean-Philippe Barnier, Ines Sayah, Youcef Bagdad, Maria A. Miteva, Michel Arthur, Mélanie Ethève-Quelquejeu, Laura Iannazzo “Ruthenium-Catalyzed Cycloaddition for Introducing Chemical Di-versity in Second generation b-Lactamase inhibitors”. ChemMedChem 2023, e202300077.
2. Rančić A., Babić N., Orio M., Peyrot F. “Structural Features Governing the Metabolic Stability of Tetraethyl-Substituted Nitroxides in Rat Liver Microsomes”  Antioxidants, 2023, 12(2), 402. DOI:  https://doi.org/10.3390/antiox12020402

1. Felder, S.; Delcourt, M.-L.; Rodríguez, R.; Favereau, L.; Jeanne Crassous, J.; Micouin, L.; Benedetti, E. “Compact CPL emitters based on a [2.2]paracyclophane scaffold: recent developments and future perspectives”, J. Mater. Chem. C 2023, 11, 2053 DOI: https://doi.org/10.1039/D2TC04885J
2. Galardon, E.; Mathas, N.; Padovani, D.; Le Corre, L.; Poncet, G.; Dairou, J. “Persulfidation of DJ-1: Mechanism and Consequences.” Biomolecules 2023, 13, 27. DOI: https://doi.org/10.3390/biom13010027
   

1. Chiara Figazzolo, Frédéric Bonhomme, Saidbakhrom Saidjalolov, Mélanie Ethève-Quelquejeu, Marcel Hollenstein “Enzymatic synthesis of vancomycin-modified DNA”, Molecule, 2022, doi.org/10.3390/molecules27248927

1. C. Kitoun, S. Saidjalolov, D. Bouquet, F. Djago, Q. Blancart Remaury, B. Sargueil, P. Poinot, Pauline; M. Etheve-Quelquejeu, L. Iannazzo “Traceless Staudinger Ligation to Access to Stable Aminoacyl- or Peptidyl-dinucleotides” ACS Omega., 2022, just accepted.
2. Rietmeyer, L.; Li de la Sierra-Gallay, I.; Schepers, G.; Dorchêne, D.; Iannazzo, L.; Patin, D.; Touzé, T.; van Tilbeurgh, H.; Herdewijn, P.; Etheve-Quelquejeu, M.; Fonvielle, M. “Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis” Nucleic Acids Research, 2022, just accepted
3. S. Felder, C. Sagné, E. Benedetti, L. Micouin “Small-Molecule 3D Ligand for RNA Recognition: Tuning Selectivity
   through Scaffold Hopping” ACS Chemical Biology, 2022, 17, 3069. DOI: https://doi.org/10.1021/acschembio.2c00171

1) J.-P. Barnier, S. Saidjalolov, F. Bouchet, L. Mayer, Z. Edoo, I. Sayah, L. Iannazzo, M.e Ethève-Quelquejeu, J.-L. Mainardi, E. Braud “Modulation of the Specificity of Carbapenems and Diazabicyclooctanes for Selective Activity against Mycobacterium tuberculosis” Antimicrob. Agents Chemother. 2022, Ahead of Print

DOI: https://doi.org/10.1128/aac.02357-21

1) F. Peyrot, S. Lajnef, D.-L. Versace. “Electron Paramagnetic Resonance Spin Trapping (EPR–ST) Technique in Photopolymerization Processes” Catalysts, 2022, 12, (7), 772; DOI: https://doi.org/10.3390/catal12070772

1) V. Meynier, L. Iannazzo, M. Catala, S. Oerum, E. Braud, C.Atdjian, P. Barraud, M. Fonvielle, C. Tisné, M.Ethève-Quelquejeu “Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase” Nucleic Acids Research, 2022, 50, (10), 5793–5806. DOI: https://doi.org/10.1093/nar/gkac354

1. M. F. Cunha,   I.Pranke, A. Sassi, C. Schreiweis, S.  Moriceau, D. Vidovic, A. Hatton, M. S. Carlon, G. Creste, F. Berhal, G. Prestat, R. Freund, N. Odolczyk, J. P. Jais, C. Gravier-Pelletier, P.  Zielenkiewicz, V. Jullien, A. Hinzpeter, F. Oury, A. Edelman, I. Sermet-Gaudelus “Systemic Bis-Phosphinic Acid Derivative Restores Chloride Transport in Cystic Fibrosis Mice” Sci Rep 2022, 12 (1), 6132. DOI: https://doi.org/10.1038/s41598-022-09678-9.
2. Li, K. Aubertin, D. Onidas, P. Nizard, N. Felidj, F. Gazeau, C. Mangeney, Y. Luo “Recent advances in non-plasmonic SERS nanostructures for biomedical applications” WIREs Nanomedicine & Nanobiotechnology 2022. DOI: https://doi.org/10.1002/wnan.1795

1) M. Oliver, L, Le Corre, M. Poinsot, M, Bosco, H. Wan, A. Amoroso, B. Joris, A. Bouhss, S. Calvet-Vitale, C. Gravier-Pelletier “A Sub-Micromolar MraYAA Inhibitor with an Aminoribosyl Uridine Structure and a (S,S)-Tartaric Diamide: Synthesis, Biological Evaluation and Molecular Modeling” Molecules 2022, 27(6), 1769. DOI:  https://doi.org/10.3390/molecules27061769

1. D. Padovani, E. Galardon, “Molecular Basis for the Interaction of Catalase with d-Penicillamine: Rationalization of Some of Its Deleterious Effects” Chem. Res. Toxicol. 2022, 35, 3, 412–421 DOI: https://doi.org/10.1021/acs.chemrestox.1c00313

1. D. R. Boyd, N. D. Sharma, P. J. Stevenson, P. Hoering, C. C. R. Allen, P. M. Dansette “Monooxygenase- and Dioxygenase-Catalyzed Oxidative Dearomatization of Thiophenes by Sulfoxidation, cis-Dihydroxylation and Epoxidation”. Int J Mol Sci. 2022, 23(2) 909. DOI:https://doi.org/10.3390/ijms23020909 
2. Li, P. Nizard, D. Onidas, A. Lamouri, J. Pinson, S. Mahouche-Chergui, K. Aubertin, F. Gazeau, Y. Luo, C. Mangeney “SERS Tags Derived from Silver Nanoparticles and Aryl Diazonium Salts for Cell Raman Imaging” Nanoscale 2022, 14, 1452. DOI: https://doi.org/10.1039/D1NR03148A
3. Bicyclic 5-5 systems with one ring junction nitrogen atom: Two extra heteroatoms 2:0 Benedetti, E.; Micouin, L. Reference Collection in Chemistry, Molecular Science and Chemical Engineering Wiley, 2022. Volume 11, pp 145-173. DOI:10.1016/B978-0-12-409547-2.14935-2 

1. S. Felder, M.-L. Delcourt, M.H.E. Bousquet, D.  Jacquemin, R. Rodríguez, L. Favereau, J. Crassous, L. Micouin, E. Benedetti “Planar chiral analogues of PRODAN based on a [2.2]paracyclophane scaffold: Synthesis and photophysical studies”. J. Org. Chem. 2021, just accepted
2. G. Kirby, L. Grimaud, M. R. Vitale,  G. Prestat, F. Berhal “Iron(ii)-catalyzed intermolecular aziridination of alkenes employing hydroxylamine derivatives as clean nitrene sources” Green Chem., 2021,23, 9428-9432. https://doi.org/10.1039/D1GC03495B
3. G. De Leener, D. Over, O. Reinaud, I. Jabin “Turning on anion and betaine hosting by a small structural change of a biomimetic cavity: a case study” Supramol. Chem. 2021, DOI: 10.1080/10610278.2021.2011890
   
4. Bitam, S.; Elbahnsi, A.; Creste, G.; Pranke, I.; Chevalier, B.; Berhal, F.; Hoffmann, B.; Servel, N.; Tondelier, D.; Hatton, A.; Moquereau, C.; Faria Da Cunha, M.; Pastor, A.; Lepissier, A.; Hinzpeter, A.; Mornon, J.-P.; Prestat, G.; Edelman, A.; Callebaut, I.; Gravier-Pelletier, C.; Sermet-Gaudelus, I. “New Insights into Structure and Function of Bis-Phosphinic Acid Derivatives and Implications for CFTR Modulation.” Sci Rep 2021, 11, 6842.
   DOI: https://doi.org/10.1038/s41598-021-83240-x
5. Bardin, E.; Pastor, A.; Semeraro, M.; Golec, A.; Hayes, K.; Chevalier, B.; Berhal, F.; Prestat, G.; Hinzpeter, A.; Gravier-Pelletier, C.; Pranke, I.; Sermet-Gaudelus, I. “Modulators of CFTR. Updates on Clinical Development and Future Directions.” Eur. J. Med. Chem. 2021, 113195  DOI: doi.org/10.1016/j.ejmech.2021.113195
6. Oliver, M.; Le Corre, L.; Poinsot, M.; Corio, A.; Madegard, L.; Bosco, M.; Amoroso, A.; Joris, B.; Auger, R.; Touzé, T.; Bouhss, A.; Calvet-Vitale, S.; Gravier-Pelletier, C.“Synthesis, biological evaluation and molecular modeling of urea-containing MraY inhibitors.”  Org. Biomol. Chem. 2021, 19(26), 5844-5866, DOI: 10.1039/D1OB00710F.
7. Pujol C, Legrand A, Parodi L, Boucher, J.-L.; Le Corre, L. et al. “Implication of folate deficiency in CYP2U1 loss of function.” J Exp Med. 2021; 218(11):e20210846. doi: 10.1084/jem.20210846.

1. S. Wu, L.A. Galan, M. Roux, F. Riobe, B. Le Guennic, Y. Guyot, T. Le Bahers, L. Micouin, O. Maury, E. Benedetti “Tuning the excited state properties of [2.2]paracyclophane-based antennas to ensure efficient sensitization of lanthanide ions or singlet oxygen generation” Inorg. Chem. 2021, 60, 16194−16203. DOI: https://doi.org/10.1021/acs.inorgchem.1c01986.
2. F. Bouchet, H. Atze,  M. Arthur, M. Etheve-Quelquejeu, L. Iannazzo “Traceless Staudinger ligation to introduce chemical diversity on β-lactamase inhibitors of second generation” Org. Lett., 2021, just accepted. 
3. Médard, X. Sun, J. Pinson, D. Li, C. Mangeney, J.-P. Michel “Electrografting and Langmuir-Blodgett: Covalently Bound Nanometer Thick Ordered Films on Graphite” Langmuir 2021, 37, 12539. DOI: https://doi.org/10.1021/acs.langmuir.1c01723

1. ​J. Haubrich, J. Font, R. B. Quast, A. Goupil-Lamy, P. Scholler, D. Nevoltris, F.Acher, P. Chames, P. Rondard, L. Prezeau, J.-P. Pin “A nanobody activating metabotropic glutamate receptor 4 discriminates between homo and heterodimers.” Proc. Natl. Acad. Sci. U S A 2021,  118 (33) e2105848118. DOI: https://doi.org/10.1073/pnas.2105848118
2. E. Brunetti, L. Marcelis, F. E. Zhurkin, M. Luhmer, I. Jabin, O. Reinaud, K. Bartik “A Water Molecule Triggers Guest Exchange at a Mono-zinc Centre Confined in a Biomimetic Calixarene Pocket: a Model for Understanding Ligand Stability in Zn Proteins” Chem. Eur. J. 2021, 27, 13730-13738 DOI:  https://doi.org/10.1002/chem.202102184.
3. Li, Y. Luo, D. Onidas, L. He, M. Jin, F. Gazeau, J. Pinson, C. Mangeney “Surface functionalization of nanomaterials by aryl diazonium salts for biomedical sciences” Adv. Colloid & Interface Science 2021, 294, 102479. DOI: https://doi.org/10.1016/j.cis.2021.102479

1. Xiao, J. Gateau, A. Brun, X. Shi, F. Gazeau, C. Mangeney, Y. Luo “Hybrid nano- and microgels doped with photoacoustic contrast agents for cancer theranostics” View 2021, 2:20200176. DOI: https://doi.org/10.1002/VIW.20200176

1. S. Felder, S. Wu, J. Brom, L. Micouin, E. Benedetti “Enantiopure planar chiral [2.2]paracyclophanes: Synthesis and applications in asymmetric organocatalysis”  Chirality, 2021, 33, 506-527 DOI: https://doi.org/10.1002/chir.23335

1. Kherbouche, D. McRae, T. Geronimi, F. Lagugné-Labarthet, A. Lamouri, A. Chevillot-Biraud, C. Mangeney, N. Felidj “Extending nanoscale patterning with multipolar surface plasmon resonances” Nanoscale 2021, 13, 11051. DOI: https://doi.org/10.1039/D1NR02181H

1. S. Felder, L. Micouin, E. Benedetti “Para‐functionalization of N‐substituted 4‐amino[2.2]paracyclophanes by regioselective formylation” Eur. J. Org. Chem., 2021, 4015-4018. DOI: https://doi.org/10.1002/ejoc.202100288
2. Barosi, A. Berisha, C. Mangeney, J. Pinson, H. Dhimane, P. I. Dalko “Efficient construction of redox responsive thin polymer layer on carbon and gold for voltage-gated delivery applications” Materials Adv. 2021, 2, 2358. DOI: https://doi.org/10.1039/D1MA00022E

1. D.A.B. Therien, D. M. McRae, C. Mangeney, N. Félidj, F. Lagugné-Labarthet “Three-Color Plasmon-Mediated Reduction of Diazonium Salts over Metasurfaces” Nanoscale Adv. 2021, 3, 2501. DOI: https://doi.org/10.1039/D0NA00862A

1. Rietmeyer, N. Fix-boulier, C. Le Fournis, L. Iannazzo, C. Kitoun, D. Patin, D. Mengin-lecreulx, M. Etheve-Quelquejeu, M. Arthur, M. Fonvielle “Partition of tRNAGly isoacceptors between protein and cell-wall peptidoglycan synthesis in Staphylococcus aureus”, Nucleic Acid Res. 2021, Accepted. DOI: http://doi.org/10.1093/nar/gkaa1242
2. S. Saidjalolov, Z. Edoo, M. Fonvielle, L. Mayer, L. Iannazzo, M. Arthur, M. Etheve-Quelquejeu, E. Braud “Synthesis of carbapenems containing peptidoglycan-mimetics and inhibition of the cross-linking activity of a transpeptidase of the L,D specificity” Chem. Eur. J., 2021, Accepted. DOI: http://doi.org/10.1002/chem.202004831
3. de Sa Nogueira D, Bourdy R, Filliol D, Quessada C, McCort-Tranchepain I, Acher F, Zwiller J, Romieu P, Befort K. “LSP2-9166, an orthosteric mGlu4 and mGlu7 receptor agonist, reduces cocaine self-administration under a progressive ratio schedule in rats” Neurosci Lett. 2020, 135603 https://doi.org/10.1016/j.neulet.2020.135603
4. K. Abbas, N. Babić, F. Peyrot. “Detection of superoxide radical in adherent living cells by electron paramagnetic resonance (EPR) spectroscopy using cyclic nitrones”. Methods Mol. Biol. 2021, 2202, 149-163. DOI: https://doi.org/10.1007/978-1-0716-0896-8_13

1. B. Li, Y. Li, C. Tomkiewicz-Raulet, P. Dao, D. Lietha, E. Yen-Pon, Z. Du, X. Coumoul, C. Garbay, M. Etheve-Quelquejeu, H. Chen “Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma” J. Med. Chem. 2020, 63, 12707-12724. DOI: 10.1021/acs.jmedchem.0c01059
2. M. Bosco, S.-J. Paik, P. Busca, S. E. H. Moore, C. Gravier-Pelletier “Synthetic Route to Glycosyl β-1C-(phosphino)-phosphonates as Unprecedented Stable Glycosyl Diphosphate Analogs and Their Preliminary Biological Evaluation” Molecules 2020, 25, 4969. DOI: 10.3390/molecules25214969
3. C. Fleurisson, E. Benedetti, L. Micouin Cyclic cis-1,3-Diamines Derived from Bicyclic Hydrazines: Synthesis and Applications Synlett 2021, 31, 858-874. DOI: 10.1055/s-0040-1707324
4. X. Chen, P. Coric, V. Larue, S. Turcaud, X. Wang, S. Nonin-Lecomte, S. Bouaziz “The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag” Eur. J. Med. Chem., 2020, 204, 112634 DOI: https://doi.org/10.1016/j.ejmech.2020.112634

1. C. Kitoun, M. Fonvielle, N. Sakkas, M. Lefresne, F. Djago, Q. Blancart Remaury, P. Poinot, M. Arthur, M. Etheve-Quelquejeu, L. Iannazzo. “Phosphine-Mediated Bioconjugation of the 3′-end of RNA” Org. Lett., 2020, Just Acccepted.   https://doi.org/10.1021/acs.orglett.0c02982
2. C. Aubry, P. Clerici, C. Gerbaud, L. Micouin, J.-L. Pernodet, S. Lautru, Revised structure of Anthelvencine A and characterization of the Anthelvencin Biosynthetic gene cluster.  ACS Chem Biol. 2020, 15, 945-951. https://doi.org/10.1021/acschembio.9b00960
3. T. Zhang, L. Le Corre, O. Reinaud, B. Colasson “A Promising Approach for Controlling the 2nd Coordination Sphere of Biomimetic Metal Complexes: Encapsulation in a Dynamic Hydrogen-Bonded Capsule” Chem. Eur. J. 2020 in press. https://doi.org/10.1002/chem.202004370.
4. J. K. Aw, K. C. Boellaard, T. K. Tan, J. Yap, Y.P. Loh, B. Colasson, È. Blanc, Y. Lam, F. M. Fung “Interacting with Three-Dimensional Molecular Structures Using an Augmented Reality Mobile App” J. Chem. Ed. 2020, 97, 3877-3881. https://doi.org/10.1021/acs.jchemed.0c00387

2) H.Liu, Ping Yi, W. Zhao, Y. Wu, F. Acher, J.-P. Pin, J. Liu and P. Rondard “Illuminating the allosteric modulation of the calcium-sensing receptor” Proc Natl Acad Sci U S A 2020, 117, 21711-21722. https://doi.org/10.1073/pnas.1922231117

3) C. Atdjian, D. Coelho, L. Iannazzo , M. Ethève-Quelquejeu, E. Braud “Synthesis of Triazole-Linked SAM-Adenosine Conjugates: Functionalization of Adenosine at N-1 or N-6 Position without Protecting Groups” Molecules 2020, 25, 3241; https://doi.org/10.3390/molecules25143241

1. N. Babić, M. Orio, F. Peyrot. “Unexpected rapid aerobic transformation of 2,2,6,6-tetraethyl-4-oxo(piperidin-1-yloxyl) radical by cytochrome P450 in the presence of NADPH: Evidence against a simple reduction of the nitroxide moiety to the hydroxylamine”. Free Radic. Biol. Med. 2020, 156, 144-156. DOI: https://doi.org/10.1016/j.freeradbiomed.2020.05.021
2. Kherbouche, Y. Luo, N. Félidj, C. Mangeney “Plasmon-Mediated Surface Functionalization: New Horizons for the Control of Surface Chemistry on the Nanoscale” Chem. Mater. 2020, 32, 5442. DOI: https://doi.org/10.1021/acs.chemmater.0c00921

1. Y. Luo, Y. Xiao, D. Onidas, L. Iannazzo, M. Ethève-Quelquejeu, A. Lamouri, N. Félidj, S. Mahouche-Chergui, T. Brulé, N. Gagey-Eilstein, F. Gazeau, C. Mangeney “Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles”.  Chem. Commun., 2020, Advance Article https://doi.org/10.1039/D0CC02842H
2. Decorbie, I. Tijunelyte, S. Gam-Derouich, J. Solard, A. Lamouri, P. Decorse, N. Felidj, C. Gauchotte-Lindsay, E. Rinnert, C. Mangeney, N. Lidgi-Guigui “Sensing Polymer/Paracetamol Interaction with an Independent Component Analysis-Based SERS-MIP Nanosensor” Plasmonics 2020, 15, 1533. DOI: https://doi.org/10.1007/s11468-020-01177-9
3. Luo, Y. Xiao, D. Onidas, L. Iannazzo, M. Ethève-Quelquejeu, A. Lamouri, N. Félidj, S. Mahouche-Chergui, T. Brulé, N. Gagey-Eilstein, F. Gazeau, C. Mangeney “Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles” Chem. Commun. 2020, 56, 6822. DOI: https://doi.org/10.1039/D0CC02842H

(2) Poirel O, Mamer LE, Herman MA, Arnulf-Kempcke M, Kervern M, Potier B, Miot S, Wang J, Favre-Besse FC, Brabet I, Laras Y, Bertrand HO, Acher F, Pin JP, Puel JL, Giros B, Epelbaum J, Rosenmund C, Dutar P, Daumas S, El Mestikawy S, Pietrancosta N. “LSP5-2157 a new inhibitor of vesicular glutamate transporters.” Neuropharmacology. 2020 164 107902. doi: 10.1016/j.neuropharm.2019.107902.

1. Médard, P. Decorse, C. Mangeney, J. Pinson, M. Fagnoni, S. Protti “Simultaneous Photografting of Two Organic Groups on a Gold Surface by using Arylazo Sulfones as Single Precursors” Langmuir 2020, 36, 11, 2786. DOI: https://doi.org/10.1021/acs.langmuir.9b03878

1. H. Habrian, J. Levitz, V. Vyklicky, Z. Fu, A.Hoagland, I. McCort-Tranchepain, F. Acher, E. Y. Isacoff “Conformational pathway provides unique sensitivity to a synaptic mGluR” Nature Commun. 2019, 10, 5572 doi:10.1038/s41467-019-13407-8
2. Abi Fayssal, A. Giungi, F. Berhal, G. Prestat “Iron-Catalyzed Intra-intermolecular Aminoazidation of Alkenes” Org. Process Res. Dev., 10.1021/acs.oprd.9b00400

N. Babić, F. Peyrot. “New synthetic route to 2,2,6,6-tetraethylpiperidin-4-one: A key-intermediate towards tetraethyl nitroxides”. Tet. Lett. 2019, 60(44), 151207. DOI: https://doi.org/10.1016/j.tetlet.2019.151207

N. Babić, F. Peyrot. “Molecular Probes for Evaluation of Oxidative Stress by In Vivo EPR Spectroscopy and Imaging: State-of-the-Art and Limitations”. Magnetochemistry 2019, I(1), 13. DOI: https://doi.org/10.3390/magnetochemistry5010013

1. Brom, J.; Maruani, A.; Micouin, L.; Benedetti, E. “Light-driven reductive cleavage of sulfonamides promoted by thiourea organophotosensitizers”. J. Org. Chem. 2023, just accepted DOI: 10.1021/acs.joc.3c00296 (Preprint ChemRxiv – DOI: 10.26434/chemrxiv-2022-jvdqw)
2. Fleurisson, C.; Graidia, N.; Foricher, Y.; Benedetti, E.; Micouin, L.;  “Intramolecular Buchwald-Hartwig N-Arylation of Bicyclic Hydrazines: Practical Access to Spiro[indoline-2,3′-piperidines]”  Org. Biomol. Chem. 2023, just accepted DOI: 10.1039/D3OB00406F (Preprint ChemRxiv – DOI: 10.26434/chemrxiv-2022-rqsqc)

1. Flavie Bouchet, Jean-Philippe Barnier, Ines Sayah, Youcef Bagdad, Maria A. Miteva, Michel Arthur, Mélanie Ethève-Quelquejeu, Laura Iannazzo “Ruthenium-Catalyzed Cycloaddition for Introducing Chemical Di-versity in Second generation b-Lactamase inhibitors”. ChemMedChem 2023, e202300077.
2. Rančić A., Babić N., Orio M., Peyrot F. “Structural Features Governing the Metabolic Stability of Tetraethyl-Substituted Nitroxides in Rat Liver Microsomes”  Antioxidants, 2023, 12(2), 402. DOI:  https://doi.org/10.3390/antiox12020402

1. Felder, S.; Delcourt, M.-L.; Rodríguez, R.; Favereau, L.; Jeanne Crassous, J.; Micouin, L.; Benedetti, E. “Compact CPL emitters based on a [2.2]paracyclophane scaffold: recent developments and future perspectives”, J. Mater. Chem. C 2023, 11, 2053 DOI: https://doi.org/10.1039/D2TC04885J
2. Galardon, E.; Mathas, N.; Padovani, D.; Le Corre, L.; Poncet, G.; Dairou, J. “Persulfidation of DJ-1: Mechanism and Consequences.” Biomolecules 2023, 13, 27. DOI: https://doi.org/10.3390/biom13010027
   

1. Chiara Figazzolo, Frédéric Bonhomme, Saidbakhrom Saidjalolov, Mélanie Ethève-Quelquejeu, Marcel Hollenstein “Enzymatic synthesis of vancomycin-modified DNA”, Molecule, 2022, doi.org/10.3390/molecules27248927

1. C. Kitoun, S. Saidjalolov, D. Bouquet, F. Djago, Q. Blancart Remaury, B. Sargueil, P. Poinot, Pauline; M. Etheve-Quelquejeu, L. Iannazzo “Traceless Staudinger Ligation to Access to Stable Aminoacyl- or Peptidyl-dinucleotides” ACS Omega., 2022, just accepted.
2. Rietmeyer, L.; Li de la Sierra-Gallay, I.; Schepers, G.; Dorchêne, D.; Iannazzo, L.; Patin, D.; Touzé, T.; van Tilbeurgh, H.; Herdewijn, P.; Etheve-Quelquejeu, M.; Fonvielle, M. “Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis” Nucleic Acids Research, 2022, just accepted
3. S. Felder, C. Sagné, E. Benedetti, L. Micouin “Small-Molecule 3D Ligand for RNA Recognition: Tuning Selectivity
   through Scaffold Hopping” ACS Chemical Biology, 2022, 17, 3069. DOI: https://doi.org/10.1021/acschembio.2c00171

1) J.-P. Barnier, S. Saidjalolov, F. Bouchet, L. Mayer, Z. Edoo, I. Sayah, L. Iannazzo, M.e Ethève-Quelquejeu, J.-L. Mainardi, E. Braud “Modulation of the Specificity of Carbapenems and Diazabicyclooctanes for Selective Activity against Mycobacterium tuberculosis” Antimicrob. Agents Chemother. 2022, Ahead of Print

DOI: https://doi.org/10.1128/aac.02357-21

1) F. Peyrot, S. Lajnef, D.-L. Versace. “Electron Paramagnetic Resonance Spin Trapping (EPR–ST) Technique in Photopolymerization Processes” Catalysts, 2022, 12, (7), 772; DOI: https://doi.org/10.3390/catal12070772

1) V. Meynier, L. Iannazzo, M. Catala, S. Oerum, E. Braud, C.Atdjian, P. Barraud, M. Fonvielle, C. Tisné, M.Ethève-Quelquejeu “Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase” Nucleic Acids Research, 2022, 50, (10), 5793–5806. DOI: https://doi.org/10.1093/nar/gkac354

1. M. F. Cunha,   I.Pranke, A. Sassi, C. Schreiweis, S.  Moriceau, D. Vidovic, A. Hatton, M. S. Carlon, G. Creste, F. Berhal, G. Prestat, R. Freund, N. Odolczyk, J. P. Jais, C. Gravier-Pelletier, P.  Zielenkiewicz, V. Jullien, A. Hinzpeter, F. Oury, A. Edelman, I. Sermet-Gaudelus “Systemic Bis-Phosphinic Acid Derivative Restores Chloride Transport in Cystic Fibrosis Mice” Sci Rep 2022, 12 (1), 6132. DOI: https://doi.org/10.1038/s41598-022-09678-9.
2. Li, K. Aubertin, D. Onidas, P. Nizard, N. Felidj, F. Gazeau, C. Mangeney, Y. Luo “Recent advances in non-plasmonic SERS nanostructures for biomedical applications” WIREs Nanomedicine & Nanobiotechnology 2022. DOI: https://doi.org/10.1002/wnan.1795

1) M. Oliver, L, Le Corre, M. Poinsot, M, Bosco, H. Wan, A. Amoroso, B. Joris, A. Bouhss, S. Calvet-Vitale, C. Gravier-Pelletier “A Sub-Micromolar MraYAA Inhibitor with an Aminoribosyl Uridine Structure and a (S,S)-Tartaric Diamide: Synthesis, Biological Evaluation and Molecular Modeling” Molecules 2022, 27(6), 1769. DOI:  https://doi.org/10.3390/molecules27061769

1. D. Padovani, E. Galardon, “Molecular Basis for the Interaction of Catalase with d-Penicillamine: Rationalization of Some of Its Deleterious Effects” Chem. Res. Toxicol. 2022, 35, 3, 412–421 DOI: https://doi.org/10.1021/acs.chemrestox.1c00313

1. D. R. Boyd, N. D. Sharma, P. J. Stevenson, P. Hoering, C. C. R. Allen, P. M. Dansette “Monooxygenase- and Dioxygenase-Catalyzed Oxidative Dearomatization of Thiophenes by Sulfoxidation, cis-Dihydroxylation and Epoxidation”. Int J Mol Sci. 2022, 23(2) 909. DOI:https://doi.org/10.3390/ijms23020909 
2. Li, P. Nizard, D. Onidas, A. Lamouri, J. Pinson, S. Mahouche-Chergui, K. Aubertin, F. Gazeau, Y. Luo, C. Mangeney “SERS Tags Derived from Silver Nanoparticles and Aryl Diazonium Salts for Cell Raman Imaging” Nanoscale 2022, 14, 1452. DOI: https://doi.org/10.1039/D1NR03148A
3. Bicyclic 5-5 systems with one ring junction nitrogen atom: Two extra heteroatoms 2:0 Benedetti, E.; Micouin, L. Reference Collection in Chemistry, Molecular Science and Chemical Engineering Wiley, 2022. Volume 11, pp 145-173. DOI:10.1016/B978-0-12-409547-2.14935-2 

1. S. Felder, M.-L. Delcourt, M.H.E. Bousquet, D.  Jacquemin, R. Rodríguez, L. Favereau, J. Crassous, L. Micouin, E. Benedetti “Planar chiral analogues of PRODAN based on a [2.2]paracyclophane scaffold: Synthesis and photophysical studies”. J. Org. Chem. 2021, just accepted
2. G. Kirby, L. Grimaud, M. R. Vitale,  G. Prestat, F. Berhal “Iron(ii)-catalyzed intermolecular aziridination of alkenes employing hydroxylamine derivatives as clean nitrene sources” Green Chem., 2021,23, 9428-9432. https://doi.org/10.1039/D1GC03495B
3. G. De Leener, D. Over, O. Reinaud, I. Jabin “Turning on anion and betaine hosting by a small structural change of a biomimetic cavity: a case study” Supramol. Chem. 2021, DOI: 10.1080/10610278.2021.2011890
   
4. Bitam, S.; Elbahnsi, A.; Creste, G.; Pranke, I.; Chevalier, B.; Berhal, F.; Hoffmann, B.; Servel, N.; Tondelier, D.; Hatton, A.; Moquereau, C.; Faria Da Cunha, M.; Pastor, A.; Lepissier, A.; Hinzpeter, A.; Mornon, J.-P.; Prestat, G.; Edelman, A.; Callebaut, I.; Gravier-Pelletier, C.; Sermet-Gaudelus, I. “New Insights into Structure and Function of Bis-Phosphinic Acid Derivatives and Implications for CFTR Modulation.” Sci Rep 2021, 11, 6842.
   DOI: https://doi.org/10.1038/s41598-021-83240-x
5. Bardin, E.; Pastor, A.; Semeraro, M.; Golec, A.; Hayes, K.; Chevalier, B.; Berhal, F.; Prestat, G.; Hinzpeter, A.; Gravier-Pelletier, C.; Pranke, I.; Sermet-Gaudelus, I. “Modulators of CFTR. Updates on Clinical Development and Future Directions.” Eur. J. Med. Chem. 2021, 113195  DOI: doi.org/10.1016/j.ejmech.2021.113195
6. Oliver, M.; Le Corre, L.; Poinsot, M.; Corio, A.; Madegard, L.; Bosco, M.; Amoroso, A.; Joris, B.; Auger, R.; Touzé, T.; Bouhss, A.; Calvet-Vitale, S.; Gravier-Pelletier, C.“Synthesis, biological evaluation and molecular modeling of urea-containing MraY inhibitors.”  Org. Biomol. Chem. 2021, 19(26), 5844-5866, DOI: 10.1039/D1OB00710F.
7. Pujol C, Legrand A, Parodi L, Boucher, J.-L.; Le Corre, L. et al. “Implication of folate deficiency in CYP2U1 loss of function.” J Exp Med. 2021; 218(11):e20210846. doi: 10.1084/jem.20210846.

1. S. Wu, L.A. Galan, M. Roux, F. Riobe, B. Le Guennic, Y. Guyot, T. Le Bahers, L. Micouin, O. Maury, E. Benedetti “Tuning the excited state properties of [2.2]paracyclophane-based antennas to ensure efficient sensitization of lanthanide ions or singlet oxygen generation” Inorg. Chem. 2021, 60, 16194−16203. DOI: https://doi.org/10.1021/acs.inorgchem.1c01986.
2. F. Bouchet, H. Atze,  M. Arthur, M. Etheve-Quelquejeu, L. Iannazzo “Traceless Staudinger ligation to introduce chemical diversity on β-lactamase inhibitors of second generation” Org. Lett., 2021, just accepted. 
3. Médard, X. Sun, J. Pinson, D. Li, C. Mangeney, J.-P. Michel “Electrografting and Langmuir-Blodgett: Covalently Bound Nanometer Thick Ordered Films on Graphite” Langmuir 2021, 37, 12539. DOI: https://doi.org/10.1021/acs.langmuir.1c01723

1. ​J. Haubrich, J. Font, R. B. Quast, A. Goupil-Lamy, P. Scholler, D. Nevoltris, F.Acher, P. Chames, P. Rondard, L. Prezeau, J.-P. Pin “A nanobody activating metabotropic glutamate receptor 4 discriminates between homo and heterodimers.” Proc. Natl. Acad. Sci. U S A 2021,  118 (33) e2105848118. DOI: https://doi.org/10.1073/pnas.2105848118
2. E. Brunetti, L. Marcelis, F. E. Zhurkin, M. Luhmer, I. Jabin, O. Reinaud, K. Bartik “A Water Molecule Triggers Guest Exchange at a Mono-zinc Centre Confined in a Biomimetic Calixarene Pocket: a Model for Understanding Ligand Stability in Zn Proteins” Chem. Eur. J. 2021, 27, 13730-13738 DOI:  https://doi.org/10.1002/chem.202102184.
3. Li, Y. Luo, D. Onidas, L. He, M. Jin, F. Gazeau, J. Pinson, C. Mangeney “Surface functionalization of nanomaterials by aryl diazonium salts for biomedical sciences” Adv. Colloid & Interface Science 2021, 294, 102479. DOI: https://doi.org/10.1016/j.cis.2021.102479

1. Xiao, J. Gateau, A. Brun, X. Shi, F. Gazeau, C. Mangeney, Y. Luo “Hybrid nano- and microgels doped with photoacoustic contrast agents for cancer theranostics” View 2021, 2:20200176. DOI: https://doi.org/10.1002/VIW.20200176

1. S. Felder, S. Wu, J. Brom, L. Micouin, E. Benedetti “Enantiopure planar chiral [2.2]paracyclophanes: Synthesis and applications in asymmetric organocatalysis”  Chirality, 2021, 33, 506-527 DOI: https://doi.org/10.1002/chir.23335

1. Kherbouche, D. McRae, T. Geronimi, F. Lagugné-Labarthet, A. Lamouri, A. Chevillot-Biraud, C. Mangeney, N. Felidj “Extending nanoscale patterning with multipolar surface plasmon resonances” Nanoscale 2021, 13, 11051. DOI: https://doi.org/10.1039/D1NR02181H

1. S. Felder, L. Micouin, E. Benedetti “Para‐functionalization of N‐substituted 4‐amino[2.2]paracyclophanes by regioselective formylation” Eur. J. Org. Chem., 2021, 4015-4018. DOI: https://doi.org/10.1002/ejoc.202100288
2. Barosi, A. Berisha, C. Mangeney, J. Pinson, H. Dhimane, P. I. Dalko “Efficient construction of redox responsive thin polymer layer on carbon and gold for voltage-gated delivery applications” Materials Adv. 2021, 2, 2358. DOI: https://doi.org/10.1039/D1MA00022E

1. D.A.B. Therien, D. M. McRae, C. Mangeney, N. Félidj, F. Lagugné-Labarthet “Three-Color Plasmon-Mediated Reduction of Diazonium Salts over Metasurfaces” Nanoscale Adv. 2021, 3, 2501. DOI: https://doi.org/10.1039/D0NA00862A

1. Rietmeyer, N. Fix-boulier, C. Le Fournis, L. Iannazzo, C. Kitoun, D. Patin, D. Mengin-lecreulx, M. Etheve-Quelquejeu, M. Arthur, M. Fonvielle “Partition of tRNAGly isoacceptors between protein and cell-wall peptidoglycan synthesis in Staphylococcus aureus”, Nucleic Acid Res. 2021, Accepted. DOI: http://doi.org/10.1093/nar/gkaa1242
2. S. Saidjalolov, Z. Edoo, M. Fonvielle, L. Mayer, L. Iannazzo, M. Arthur, M. Etheve-Quelquejeu, E. Braud “Synthesis of carbapenems containing peptidoglycan-mimetics and inhibition of the cross-linking activity of a transpeptidase of the L,D specificity” Chem. Eur. J., 2021, Accepted. DOI: http://doi.org/10.1002/chem.202004831
3. de Sa Nogueira D, Bourdy R, Filliol D, Quessada C, McCort-Tranchepain I, Acher F, Zwiller J, Romieu P, Befort K. “LSP2-9166, an orthosteric mGlu4 and mGlu7 receptor agonist, reduces cocaine self-administration under a progressive ratio schedule in rats” Neurosci Lett. 2020, 135603 https://doi.org/10.1016/j.neulet.2020.135603
4. K. Abbas, N. Babić, F. Peyrot. “Detection of superoxide radical in adherent living cells by electron paramagnetic resonance (EPR) spectroscopy using cyclic nitrones”. Methods Mol. Biol. 2021, 2202, 149-163. DOI: https://doi.org/10.1007/978-1-0716-0896-8_13

1. B. Li, Y. Li, C. Tomkiewicz-Raulet, P. Dao, D. Lietha, E. Yen-Pon, Z. Du, X. Coumoul, C. Garbay, M. Etheve-Quelquejeu, H. Chen “Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma” J. Med. Chem. 2020, 63, 12707-12724. DOI: 10.1021/acs.jmedchem.0c01059
2. M. Bosco, S.-J. Paik, P. Busca, S. E. H. Moore, C. Gravier-Pelletier “Synthetic Route to Glycosyl β-1C-(phosphino)-phosphonates as Unprecedented Stable Glycosyl Diphosphate Analogs and Their Preliminary Biological Evaluation” Molecules 2020, 25, 4969. DOI: 10.3390/molecules25214969
3. C. Fleurisson, E. Benedetti, L. Micouin Cyclic cis-1,3-Diamines Derived from Bicyclic Hydrazines: Synthesis and Applications Synlett 2021, 31, 858-874. DOI: 10.1055/s-0040-1707324
4. X. Chen, P. Coric, V. Larue, S. Turcaud, X. Wang, S. Nonin-Lecomte, S. Bouaziz “The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag” Eur. J. Med. Chem., 2020, 204, 112634 DOI: https://doi.org/10.1016/j.ejmech.2020.112634

1. C. Kitoun, M. Fonvielle, N. Sakkas, M. Lefresne, F. Djago, Q. Blancart Remaury, P. Poinot, M. Arthur, M. Etheve-Quelquejeu, L. Iannazzo. “Phosphine-Mediated Bioconjugation of the 3′-end of RNA” Org. Lett., 2020, Just Acccepted.   https://doi.org/10.1021/acs.orglett.0c02982
2. C. Aubry, P. Clerici, C. Gerbaud, L. Micouin, J.-L. Pernodet, S. Lautru, Revised structure of Anthelvencine A and characterization of the Anthelvencin Biosynthetic gene cluster.  ACS Chem Biol. 2020, 15, 945-951. https://doi.org/10.1021/acschembio.9b00960
3. T. Zhang, L. Le Corre, O. Reinaud, B. Colasson “A Promising Approach for Controlling the 2nd Coordination Sphere of Biomimetic Metal Complexes: Encapsulation in a Dynamic Hydrogen-Bonded Capsule” Chem. Eur. J. 2020 in press. https://doi.org/10.1002/chem.202004370.
4. J. K. Aw, K. C. Boellaard, T. K. Tan, J. Yap, Y.P. Loh, B. Colasson, È. Blanc, Y. Lam, F. M. Fung “Interacting with Three-Dimensional Molecular Structures Using an Augmented Reality Mobile App” J. Chem. Ed. 2020, 97, 3877-3881. https://doi.org/10.1021/acs.jchemed.0c00387

2) H.Liu, Ping Yi, W. Zhao, Y. Wu, F. Acher, J.-P. Pin, J. Liu and P. Rondard “Illuminating the allosteric modulation of the calcium-sensing receptor” Proc Natl Acad Sci U S A 2020, 117, 21711-21722. https://doi.org/10.1073/pnas.1922231117

3) C. Atdjian, D. Coelho, L. Iannazzo , M. Ethève-Quelquejeu, E. Braud “Synthesis of Triazole-Linked SAM-Adenosine Conjugates: Functionalization of Adenosine at N-1 or N-6 Position without Protecting Groups” Molecules 2020, 25, 3241; https://doi.org/10.3390/molecules25143241

1. N. Babić, M. Orio, F. Peyrot. “Unexpected rapid aerobic transformation of 2,2,6,6-tetraethyl-4-oxo(piperidin-1-yloxyl) radical by cytochrome P450 in the presence of NADPH: Evidence against a simple reduction of the nitroxide moiety to the hydroxylamine”. Free Radic. Biol. Med. 2020, 156, 144-156. DOI: https://doi.org/10.1016/j.freeradbiomed.2020.05.021
2. Kherbouche, Y. Luo, N. Félidj, C. Mangeney “Plasmon-Mediated Surface Functionalization: New Horizons for the Control of Surface Chemistry on the Nanoscale” Chem. Mater. 2020, 32, 5442. DOI: https://doi.org/10.1021/acs.chemmater.0c00921

1. Y. Luo, Y. Xiao, D. Onidas, L. Iannazzo, M. Ethève-Quelquejeu, A. Lamouri, N. Félidj, S. Mahouche-Chergui, T. Brulé, N. Gagey-Eilstein, F. Gazeau, C. Mangeney “Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles”.  Chem. Commun., 2020, Advance Article https://doi.org/10.1039/D0CC02842H
2. Decorbie, I. Tijunelyte, S. Gam-Derouich, J. Solard, A. Lamouri, P. Decorse, N. Felidj, C. Gauchotte-Lindsay, E. Rinnert, C. Mangeney, N. Lidgi-Guigui “Sensing Polymer/Paracetamol Interaction with an Independent Component Analysis-Based SERS-MIP Nanosensor” Plasmonics 2020, 15, 1533. DOI: https://doi.org/10.1007/s11468-020-01177-9
3. Luo, Y. Xiao, D. Onidas, L. Iannazzo, M. Ethève-Quelquejeu, A. Lamouri, N. Félidj, S. Mahouche-Chergui, T. Brulé, N. Gagey-Eilstein, F. Gazeau, C. Mangeney “Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles” Chem. Commun. 2020, 56, 6822. DOI: https://doi.org/10.1039/D0CC02842H

(2) Poirel O, Mamer LE, Herman MA, Arnulf-Kempcke M, Kervern M, Potier B, Miot S, Wang J, Favre-Besse FC, Brabet I, Laras Y, Bertrand HO, Acher F, Pin JP, Puel JL, Giros B, Epelbaum J, Rosenmund C, Dutar P, Daumas S, El Mestikawy S, Pietrancosta N. “LSP5-2157 a new inhibitor of vesicular glutamate transporters.” Neuropharmacology. 2020 164 107902. doi: 10.1016/j.neuropharm.2019.107902.

1. Médard, P. Decorse, C. Mangeney, J. Pinson, M. Fagnoni, S. Protti “Simultaneous Photografting of Two Organic Groups on a Gold Surface by using Arylazo Sulfones as Single Precursors” Langmuir 2020, 36, 11, 2786. DOI: https://doi.org/10.1021/acs.langmuir.9b03878

1. H. Habrian, J. Levitz, V. Vyklicky, Z. Fu, A.Hoagland, I. McCort-Tranchepain, F. Acher, E. Y. Isacoff “Conformational pathway provides unique sensitivity to a synaptic mGluR” Nature Commun. 2019, 10, 5572 doi:10.1038/s41467-019-13407-8
2. Abi Fayssal, A. Giungi, F. Berhal, G. Prestat “Iron-Catalyzed Intra-intermolecular Aminoazidation of Alkenes” Org. Process Res. Dev., 10.1021/acs.oprd.9b00400

N. Babić, F. Peyrot. “New synthetic route to 2,2,6,6-tetraethylpiperidin-4-one: A key-intermediate towards tetraethyl nitroxides”. Tet. Lett. 2019, 60(44), 151207. DOI: https://doi.org/10.1016/j.tetlet.2019.151207

N. Babić, F. Peyrot. “Molecular Probes for Evaluation of Oxidative Stress by In Vivo EPR Spectroscopy and Imaging: State-of-the-Art and Limitations”. Magnetochemistry 2019, I(1), 13. DOI: https://doi.org/10.3390/magnetochemistry5010013