Recent Publications

S. Felder, L. Micouin, E. Benedetti “Para‐functionalization of N‐substituted 4‐amino[2.2]paracyclophanes by regioselective formylation” Eur. J. Org. Chem., 2021, Accepted. DOI: https://doi.org/10.1002/ejoc.202100288

1. Rietmeyer, N. Fix-boulier, C. Le Fournis, L. Iannazzo, C. Kitoun, D. Patin, D. Mengin-lecreulx, M. Etheve-Quelquejeu, M. Arthur, M. Fonvielle “Partition of tRNAGly isoacceptors between protein and cell-wall peptidoglycan synthesis in Staphylococcus aureus”, Nucleic Acid Res. 2021, Accepted. DOI: http://doi.org/10.1093/nar/gkaa1242
2. S. Saidjalolov, Z. Edoo, M. Fonvielle, L. Mayer, L. Iannazzo, M. Arthur, M. Etheve-Quelquejeu, E. Braud “Synthesis of carbapenems containing peptidoglycan-mimetics and inhibition of the cross-linking activity of a transpeptidase of the L,D specificity” Chem. Eur. J., 2021, Accepted. DOI: http://doi.org/10.1002/chem.202004831

    

1. B. Li, Y. Li, C. Tomkiewicz-Raulet, P. Dao, D. Lietha, E. Yen-Pon, Z. Du, X. Coumoul, C. Garbay, M. Etheve-Quelquejeu, H. Chen “Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma” J. Med. Chem. 2020, 63, 12707-12724. DOI: 10.1021/acs.jmedchem.0c01059
2. M. Bosco, S.-J. Paik, P. Busca, S. E. H. Moore, C. Gravier-Pelletier “Synthetic Route to Glycosyl β-1C-(phosphino)-phosphonates as Unprecedented Stable Glycosyl Diphosphate Analogs and Their Preliminary Biological Evaluation” Molecules 2020, 25, 4969. DOI: 10.3390/molecules25214969
3. C. Fleurisson, E. Benedetti, L. Micouin Cyclic cis-1,3-Diamines Derived from Bicyclic Hydrazines: Synthesis and Applications Synlett published online. DOI: 10.1055/s-0040-1707324
4. X. Chen, P. Coric, V. Larue, S. Turcaud, X. Wang, S. Nonin-Lecomte, S. Bouaziz “The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag” Eur. J. Med. Chem., 2020, 204, 112634 DOI: https://doi.org/10.1016/j.ejmech.2020.112634

1. C. Kitoun, M. Fonvielle, N. Sakkas, M. Lefresne, F. Djago, Q. Blancart Remaury, P. Poinot, M. Arthur, M. Etheve-Quelquejeu, L. Iannazzo. “Phosphine-Mediated Bioconjugation of the 3′-end of RNA” Org. Lett., 2020, Just Acccepted.   https://doi.org/10.1021/acs.orglett.0c02982
2. C. Aubry, P. Clerici, C. Gerbaud, L. Micouin, J.-L. Pernodet, S. Lautru, Revised structure of Anthelvencine A and characterization of the Anthelvencin Biosynthetic gene cluster.  ACS Chem Biol. 2020, 15, 945-951. https://doi.org/10.1021/acschembio.9b00960
3. T. Zhang, L. Le Corre, O. Reinaud, B. Colasson “A Promising Approach for Controlling the 2nd Coordination Sphere of Biomimetic Metal Complexes: Encapsulation in a Dynamic Hydrogen-Bonded Capsule” Chem. Eur. J. 2020 in press. https://doi.org/10.1002/chem.202004370.
4. J. K. Aw, K. C. Boellaard, T. K. Tan, J. Yap, Y.P. Loh, B. Colasson, È. Blanc, Y. Lam, F. M. Fung “Interacting with Three-Dimensional Molecular Structures Using an Augmented Reality Mobile App” J. Chem. Ed. 2020, 97, 3877-3881. https://doi.org/10.1021/acs.jchemed.0c00387

1) Dubois L, Pietrancosta N, Cabaye A, Fanget I, Debacker C, Gilormini PA, Dansette PM, Dairou J, Biot C, Froissart R, Goupil-Lamy A, Bertrand HO, Acher FC, McCort-Tranchepain I, Gasnier B, Anne C. “Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin.” J. Med. Chem. 2020  Online ahead of print.  https://doi.org/10.1021/acs.jmedchem.9b02119.  PMID: 32608236

2) H.Liu, Ping Yi, W. Zhao, Y. Wu, F. Acher, J.-P. Pin, J. Liu and P. Rondard “Illuminating the allosteric modulation of the calcium-sensing receptor” PNAS Just Accepted article

3) C. Atdjian, D. Coelho, L. Iannazzo , M. Ethève-Quelquejeu, E. Braud “Synthesis of Triazole-Linked SAM-Adenosine Conjugates: Functionalization of Adenosine at N-1 or N-6 Position without Protecting Groups” Molecules 2020, 25, 3241; https://doi.org/10.3390/molecules25143241

(1) Y. Luo, Y. Xiao, D. Onidas, L. Iannazzo, M. Ethève-Quelquejeu, A. Lamouri, N. Félidj, S. Mahouche-Chergui, T. Brulé, N. Gagey-Eilstein, F. Gazeau, C. Mangeney “Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles”.  Chem. Commun., 2020, Advance Article https://doi.org/10.1039/D0CC02842H

(1) Flavie Bouchet, Heiner Atze, Matthieu Fonvielle, Zainab Edoo, Michel Arthur, Mélanie Ethève-Quelquejeu, Laura Iannazzo “Diazabicyclooctane functionalization for inhibition of β-lactamases from enterobacteria”. Journal of Medicinal Chemistry, Just Accepted, https://doi.org/10.1021/acs.jmedchem.9b02125

(1) A. Mikou, A. Cabayé, A. Goupil, H.-O. Bertrand, J.-P. Mothet, F. Acher “Asc-1 Transporter (SLC7A10): Homology models and molecular dynamics insights into the first steps of the transport mechanism.” Sci.Rep. DOI: doi.org/10.1038/s41598-020-60617-y

(2) Poirel O, Mamer LE, Herman MA, Arnulf-Kempcke M, Kervern M, Potier B, Miot S, Wang J, Favre-Besse FC, Brabet I, Laras Y, Bertrand HO, Acher F, Pin JP, Puel JL, Giros B, Epelbaum J, Rosenmund C, Dutar P, Daumas S, El Mestikawy S, Pietrancosta N. “LSP5-2157 a new inhibitor of vesicular glutamate transporters.” Neuropharmacology. 2020 164 107902. doi: 10.1016/j.neuropharm.2019.107902.

B. Colasson, A. Credi, B. Ventura “Photoinduced electron transfer involving a naphthalimide chromophore in switchable and flexible [2]rotaxanes“ Chem. Eur. J., 2020, 26, 534-542. doi: 10.1002/chem.201904155.

Zahim, D. Ajami, P. Laurent, H. Valkenier, O. Reinaud, M. Luhmer, I. Jabin ” Synthesis and Binding Properties of a Tren-Capped Hexahomotrioxacalix[3]arene” ChemPhysChem 10.1002/cphc.201900951

Hayek, N. Pietrancosta, A. A. Hovhannisyan, R. Alves de Sousa N. Bekaddour, L. Ermellino, E. Tramontano, S. Arnould, C. Sardet, J. Dairou, O. Diaz, V. Lotteau, S. Nisole, G. Melikyan, J.-H. Herbeuval, P.- O. Vidalain. “Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition” Eur. J. Med. Chem. DOI: 10.1016/j.ejmech.2019.111855

1. H. Habrian, J. Levitz, V. Vyklicky, Z. Fu, A.Hoagland, I. McCort-Tranchepain, F. Acher, E. Y. Isacoff “Conformational pathway provides unique sensitivity to a synaptic mGluR” Nature Commun. 2019, 10, 5572 doi:10.1038/s41467-019-13407-8
2. Abi Fayssal, A. Giungi, F. Berhal, G. Prestat “Iron-Catalyzed Intra-intermolecular Aminoazidation of Alkenes” Org. Process Res. Dev., 10.1021/acs.oprd.9b00400