cedric
Cédric CARADEUC
Assistant Engineer
Bio-Spectroscopy
cedric.caradeuc@u-paris.fr
+33 1 76 53 42 58, room R172/175/176
Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques (LCBPT)
CNRS UMR 8601
Université de Paris, Campus Saint-Germain-des-Prés
45 Rue des Saints Pères
75006, Paris, France
Biography
Cédric CARADEUC graduated University Institute of Technology of chemistry from Rennes in 2013. He specializes in 2014 in analytical chemistry with a professional license from the IUT of Orsay completed with work-study experience in the NMR team of SANOFI in Chilly-Mazarin over a project of pure shift NMR on 2D experiment.
In 2015, he moved to the Université Paris Cité where he became assistant engineer in the NMR of Biological Substances team as operational manager of the NMR platform in the Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicicologues (UMR8601 CNRS). In 2024, he obtained a master’s degree in chemistry from the Université Paris Cité with a Validation of Acquired Experience.
During these years, he worked in the he oversees NMR experiments for both internal research teams and external requests. He is also involved in the “MétaboParis-Santé” project, participating in research focused on NMR-based metabolomics, which includes sample preparation, data analysis, and report generation in public health research.
Publications
2024
Abi Akar E, Weill L, El Khoury M, Caradeuc C, Bertho G, Boutary S, Bezier C, Clerc Z, Sapaly D, Bendris S, Cheguillaume F, Giraud N, Eid AA, Charbonnier F, Biondi O, The analysis of the skeletal muscle metabolism is crucial for designing optimal exercise paradigms in type 2 diabetes mellitus. DOI: https://doi.org/10.1186/s10020-024-00850-7
Cabald T, Marie-Magdeleine C, Philibert L, Caradeuc C, Bertho G, Giraud N, Cebrián-Torrejón G, Sylvestre M, Phytochemical Study of the Anthelminthic Potential of Guadeloupean Plant Biodiversity. DOI: https://doi.org/10.3390/ph17060774
Dos Santos K, Bartocci A, Gillet N, Denis-Quanquin S, Roux A, Lin E, Xu Z, Finizola R, Chedozeau P, Chen X, Caradeuc C, Baudin M, Bertho G, Riobé F, Maury O, Dumont E, Giraud N, One touch is all it takes: the supramolecular interaction between ubiquitin and lanthanide complexes revisited by paramagnetic NMR and molecular dynamics. DOI: https://doi.org/10.1039/d4cp00463a
2023
K. Dos Santos, G. Bertho , C. Caradeuc, V. Baud, A. Montagne, D. Abergel, N. Giraud, M. Baudin, A Toolbox For Glutamine Use In Dissolution Dynamic Nuclear Polarization: From Enzymatic Reaction Monitoring To The Study Of Cellular Metabolic Pathways And Imaging. Chemphyschem. 2023 Mar 27:e202300151. doi: 10.1002/cphc.202300151. Epub ahead of print. PMID: 36973178.
Covadonga Lucas-Torres, Cédric Caradeuc, Laura Prieur, Haidar Djemai, Layale Youssef, Philippe Noirez, Xavier Coumoul, Karine Audouze, Nicolas Giraud, Gildas Bertho, NMR metabolomics study of chronic low-dose exposure to a cocktail of persistent organic pollutants DOI: https://doi.org/10.1002/nbm.5006
Chen X, Bertho G, Caradeuc C, Giraud N, Lucas-Torres C, Present and future of pure shift NMR in metabolomics DOI: https://doi.org/10.1002/mrc.5356
2022
G. Bertho, L. Lordello, X. Chen, C. Lucas-Torres, I.-E.Oumezziane, C. Caradeuc, M. Baudin, S. Nuan-Aliman, C. Thieblemont, V. Baud, N. Giraud, Ultrahigh-Resolution NMR with Water Signal Suppression for a Deeper Understanding of the Action of Antimetabolic Drugs on Diffuse Large B-Cell Lymphoma, J. Proteome Res. 2022, 21, 4, 1041–1051, DOI: https://doi.org/10.1021/acs.jproteome.1c00914
Sancerni T, Renoult O, Luby A, Caradeuc C, Lenoir V, Croyal M, Ransy C, Aguilar E, Postic C, Bertho G, Dentin R, Prip-Buus C, Pecqueur C, Alves-Guerra MC. UCP2 silencing restrains leukemia cell proliferation through glutamine metabolic remodeling. Front Immunol. 2022 Oct 6;13:960226. DOI: 10.3389/fimmu.2022.960226.
Gildas Bertho, Imed Eddine Oumezziane, Cédric Caradeuc, Louis Guibout, Christine Balducci, Laurence Dinan, Pierre J Dilda, Serge Camelo, René Lafont, Nicolas Giraud, Structural analysis of unstable norbixin isomers guided by pure shift nuclear magnetic resonance DOI:https://doi.org/10.1002/mrc.5252
Xi Chen, C Caradeuc, A Montagne, V Baud, G Bertho, C Lucas-Torres, N Giraud, Absolute Metabolite Quantification Using Pure Shift NMR: Toward Quantitative Metabolic Profiling of Aqueous Biological Samples DOI:https://doi.org/10.1021/acs.analchem.2c02823
2021
Balducci C, Dinan L, Guibout L, Foucault AS, Carbonne C, Durand JD, Caradeuc C, Bertho G, Girault JP, Lafont R. The complex metabolism of poststerone in male rats. J Steroid Biochem Mol Biol. 2021 Sep; 212:105897. doi: 10.1016/j.jsbmb.2021.105897.
Arnould H, Baudouin V, Baudry A, Ribeiro LW, Ardila-Osorio H, Pietri M, Caradeuc C, Soultawi C, Williams D, Alvarez M, Crozet C, Djouadi F, Laforge M, Bertho G, Kellermann O, Launay JM, Schmitt-Ulms G, Schneider B. Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases. PLoS Pathog. 2021 Oct 5;17(10):e1009991. doi: 10.1371/journal.ppat.1009991
2020
Maignien C, Santulli P, Kateb F, Caradeuc C, Marcellin L, Pocate-Cheriet K, Bourdon M, Chouzenoux S, Batteux F, Bertho G, Chapron C. Endometriosis phenotypes are associated with specific serum metabolic profiles determined by proton-nuclear magnetic resonance. Reprod Biomed Online. 2020 Oct;41(4):640-652. doi: 10.1016/j.rbmo.2020.06.019
2019
2018
Baptiste Fohlen, Quentin Tavernier, Thi-Mum Huynh, Cédric Caradeuc, Delphine Le Corre, Gildas Bertho, Bernard Cholley, Nicolas Pallet Real-Time and Non-invasive Monitoring of the Activation of the IRE1α-XBP1 Pathway in Individuals with Hemodynamic Impairment DOI: 10.1016/j.ebiom.2017.12.023
2017
Desseille C, Deforges S, Biondi O, Houdebine L, D’amico D, Lamazière A, Caradeuc C, Bertho G, Bruneteau G, Weill L, Bastin J, Djouadi F, Salachas F, Lopes P, Chanoine C, Massaad C, Charbonnier F. Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice. Front Mol Neurosci. 2017 Oct 20;10:332. doi: 10.3389/fnmol.2017.00332
Luck M, Schmitt C, Talbi N, Gouya L, Caradeuc C, Puy H, Bertho G, Pallet N. Urinary metabolic profiling of asymptomatic acute intermittent porphyria using a rule-mining-based algorithm. Metabolomics. 2018;14(1):10.. Epub 2017 Dec 4. Erratum in: Metabolomics. 2018 Jan 30;14(3):21. PMID: 29416446; PMCID: PMC5794841 DOI: 10.1007/s11306-017-1305-9