Laboratoire de Chimie et Biochimie
Pharmacologiques et Toxicologiques (LCBPT)
Université Paris Descartes
45 Rue des Saints Pères
75270 Paris Cedex 06

Diana OVER

Assistant Professor

Laboratoire de Chimie et Biochimie pharmacologiques et toxicologiques (LCBPT) – CNRS UMR 8601
Université Paris Descartes
45 Rue des Saints Pères
75270 Paris Cedex 06

Curriculum Vitae

2017-présent – Membre de l’équipe de chimie bioinorganique des espèces soufrées, chimie pharmaceutique : “Intrinsic molecular properties of H2S signaling species – Synthesis of disulfanido metal complexes as stable sources of persulfides and comparison of their reactivity with that observed for thiolato complexes”.

2006-2017 – Membre de l’équipe de chimie bioinorganique supramoléculaire, Pr. Olivia Reinaud: “Synthesis of novel calix[6]cryptand ligands and their corresponding metal complexes, spectroscopic studies, host-guest behaviour and O2 activation”.

2003-2006 Enseignement à plein temps (302.5 heures / an)

2000-2003 – Membre de l’équipe du Dr. Jiri Kozelka: “Study of diamineplatinum(II)GpG chelate complexes”.

1993-2000 – Membre de l’équipe du Pr. Jean-Claude Chottard. “Copper complexes of polyimidazole and polyimidazol-sulfur ligands; model compounds for nitrile hydratase”.

Depuis 1993 Maître de Conférences, UMR-CNRS 8601, Université Paris Descartes

1992-1993 – Séjour post-doctoral au laboratoire du Dr. J.-C. Marchon, CEA, DRFM, Grenoble, France: “Study of reaction intermediates formed during the asymmetric catalysis of an epoxydation reaction by Ru-chiroporphyrins”.

1987-1992 – Ph.D. au laboratoire du Pr. J. M. Mayer, University of Washington, Seattle, U.S.A.: “Studies on Oxygen Atom and Nitrene Group Transfer: Reactions of Low Valent W(II) and Mo(II) Complexes with Amines; Mechanistic Studies on Nitrene or Oxygen Atom Transfer of Aziridines and Epoxides to W(II) Complexes; Intermetal Oxygen and Chlorine Atom Transfer Between W, Mo and Re.”

1985-1987 – Bachelor’s Degree en Biochimie, University of California, San Diego, U.S.A..

1982-1984 – Vor-Diplom en Chimie, Universität zu Köln, Germany.



G. De Leener, D. Over, S. Coryse; D. Cornut,A.-G. Porras-Gutierrez, I. López, B. Douziech, N. Le Poul, F. Topić, K. Rissanen, Y. Le Mest, I. Jabin, O. Reinaud, Inorg. Chem. 2017, 56, 10971−10983. Two-story” Calix[6]arene-based Zinc and Copper Complexes: Structure, Properties, O2 Binding.

G. De Leener, F. Evoung-Evoung, A. Lascaux, J. Mertens, A.- G. Porras-Gutierrez, N. Le Poul, C. Lagrost,D. Over, Y. R. Leroux,F. Reniers,P. Hapiot,Y. Le Mest, I. Jabin, O. Reinaud, J. Am. Chem. Soc., 2016, 138, 12841–12853. Immobilization of Monolayers Incorporating Cu Funnel Complexes onto Gold Electrodes. Application to the Selective Electrochemical Recognition of Primary Alkylamines in Water.

J.-N. Rebilly, B.,Colasson, O.Bistri, D. Over, O.Reinaud, Chem. Soc. Rev., 2015, 44, 467-489. Biomimetic Cavity-Based Metal Complexes.

D. Over, X. Zeng, C. Bornholdt, J. Marrot, O. Reinaud, Chem., 2013, 52, 14089-14095. Coordination of Lead(II) in the Supramolecular Environment Provided by a “Two-Story” Calix[6]arene-based N6 Ligand.

N. Menard, D. Over, O. Reinaud, B. Colasson, Tet. Lett., 2013, 54, 3398-3401. Proton-induced motion in a molecular cup-and-ball Zinc funnel complex.

Zeng, C. Bornholdt, D. Over, O. Reinaud, Org. Lett., 2011, 13, 5660-5663. Synthesis of ”Two-story” Calix[6]aza-cryptands.

D. Over, A. de la Lande, X. Zeng, O. Parisel, O. Reinaud, Inorg. Chem., 2009, 48, 4317-4330. Replacement of a Nitrogen by a Phosphorus Donor in Biomimetic Copper Complexes: a Surprising and Informative Case Study with Calix[6]arene-Based Cryptands.

G. Izzet, X. Zeng, D. Over, B. Douziech, J. Zeitouny, M. Giorgi, I. Jabin, Y. Le Mest, O. Reinaud, Inorg. Chem., 2007, 46, 375-377. Insights into the electronic properties of a Cu(II) center embedded in the PN3 cap of a calix[6]arene-based ligand.

D. Over, G. Bertho, M.-A.Elizondo-Riojas, J. Kozelka, J. Biol. Inorg. Chem., 2006, 11, 139-152. Fixing the conformations of diamineplatinum(II)-GpG chelates : NMR and CD signatures of individual rotamers.

S. Benazeth, J. Purans, D. E. Over, J.C. Chottard, Journal de Physique IV, 1997, 7, 639-640. Cu polyimidazole thioether complexes: Comparison of RDF’s reconstructed from XAFS and XRD data.

D. Over, M. Bardet, J. C. Marchon, R. Ramasseul, 1995, Magn. Res. Chem., 33, 224-227. Complete 1H And 13C NMR Assignments of 2 Steroid 5,6-beta-Epoxides Using 1D-TOCSY And 2D-HMQC-TOCSY Experiments.

M. Veyrat, O. Maury, F. Faverjon, D. E. Over, J. C. Marchon, R. Ramasseul, I. Turowska-Tyrc, R. Scheidt, Angew. Chem. Int. Ed. Engl., 1994, 33, 220-223. Chiroporphyrins: An Approach to Asymmetric Catalysts with Stereocenters Near the Plane of the Porphyrin Ring.

D. E. Over, J. M. Mayer, Polyhedron. 1993, 12, 2593-2602. Amine Complexes of Tungsten(II) and Molybdenum(II) – M(NH2R)Cl2(PMePh2)3 and M(NH2CH2CH2NH2)Cl2(PMePh2)2.

D. . E. Over, S. C. Critchlow, J. M. Mayer, Inorg. Chem. 1992, 31, 4643-4648. Oxygen and chlorine atom transfer between tungsten, molybdenum, and rhenium complexes. Competition between one- and two-electron pathways.

L. M. Atagi, D. E. Over, D. R. McAlister, J. M. Mayer, J. Am. Chem. Soc., 1991, 113, 870-874. On The Mechanism of Oxygen Atom or Nitrene Group Transfer in Reactions of Epoxides And Aziridines With Tungsten(II) Compounds.