Laboratoire de Chimie et Biochimie
Pharmacologiques et Toxicologiques (LCBPT)
CNRS UMR 8601
Université Paris Cité
45 Rue des Saints Pères
75270 Paris Cedex 06
France
Yun LUO
Research Scientist, CNRS
Laboratoire de Chimie et Biochimie pharmacologiques et toxicologiques (LCBPT) – CNRS UMR 8601
Université Paris Cité
45 Rue des Saints Pères
75270 Paris Cedex 06
France
Biography
After completing my master training in analytical chemistry at Sichuan University in China, I embarked on my research journey in 2008, by pursuing a PhD in materials chemistry. Over 3 years, I focused on lanthanide-based metal organic framework (MOF) as anticounterfeiting taggants, under supervising of Prof. Carole Daiguebonne in INSA de Rennes (France). In 2012, I began my first post-doctoral research in University of Rennes 1 (France), under guidance of Dr. Bruno Fabre. Here I delved into surface functionalization of silicon for electrocatalytical artificial photosynthesis (i.e. photoelectrocatalytical reduction of CO2). Moving forward, in 2013, I joined Prof. Nicolas Alonso-Vante’s group in University of Poitiers (France), working on advanced nanoalloys and nanocomposites for cathodic reaction (i.e. oxygen reduction reaction, ORR) of fuel cells. In 2016, I accepted an Associate Professor position in South China University of Technology (China), concentrating on nanomaterials for energy conversion. One year later, I returned to France for family reason and assumed temporary lecturer and research assistant in Paris Cité University. Working with Prof. Claire Mangeney, I have focused on surface functionalization of nanomaterials for biomedical applications (e.g. biosensing and cancer theranostics), employing an innovative surface strategy using aryl diazonium salts as coupling agents. Since 2019, I have held a tenured researcher position (CRCN) at CNRS in LCBPT lab at Paris Cité University, working at the intersection at surface chemistry, nanoscience and biomedicine. Since 2019, I have secured six granted fundings, leading three research projects as the PI in the fields of bioresorbable stents, nanooptics, and cancer theranostics, also contributing as a collaborator in three additional projects in the field of biosensing and bioimaging.
Curriculum Vitae
ORCID 0000-0002-9515-0460
https://scholar.google.fr/citations?us er=wWChhMUAAAAJ&hl=fr
27/02/2024 Research Director Habilitation (HDR), Université Paris Cité
2019 – now Tenured Researcher (CRCN) at The French National Centre for Scientific Research (CNRS)
Team leader of Nano Bio Spectroscopy, Laboratory of Pharmacological and Toxicological Chemistry and Biochemistry – LCBPT UMR 8601 / Faculty of Fundamental and Biomedical Sciences, Paris Cité University / CNRS / France
2017 – 2019 Temporary Lecturer and Research Assistant (ATER)
Faculty of Fundamental and Biomedical Sciences, Paris Cité University / CNRS / France
2016 – 2017 Associate Professor
School of Environment and Energy, South China University of Technology / P.R. China
2013 – 2015 Post-doc
Institute of Environment and Materials Chemistry of Poitiers – IC2MP UMR 7285, University of Poitiers / CNRS / France
2012 – 2013 Post-doc
Rennes Institute of Chemical Sciences – ISCR UMR 6226, University of Rennes 1 / CNRS / France
06/06/2012 PhD in chemistry supervised by Prof. Carole Daiguebonne
Rennes Institute of Chemical Sciences – ISCR UMR 6226, The National Institute of Applied Sciences of Rennes (INSA Rennes) / France
2008 Master in chemistry
College of Chemistry, Sichuan University / P. R. China
Granted projects
2021-2025 (on-going). As Coordinator: Controlled degradation behavior of bioresorbable stent via surface strategy – BIORESORB. Young Researchers Program (JCJC), The French National Research Agency (ANR).
2019-2020. As Coordinator: NIR-laser-switched smart nanocomposites as dual contrast agents for photoacoustic and Raman imaging and photothermally-activated drug-delivery systems. CNRS starter funding.
2022-2025 (on-going). As local principal investigator: Spectrally tunable advanced nanosource for local spectroscopy – ADVANSPEC. Collaborative research program (PRC), ANR. Coordinator: Pierre-Michel Adam.
2020-2022. As collaborator: Translating synovial fluid biomarkers to diagnoses using nanospectroscopy – SYNOFLUID. Manifestation d’Intérêt Prématuration IdEx, Université Paris Cité. Coordinator: Claire Mangeney and Christelle Nguyen.
2019-2020. As collaborator: New generation of fluorine-19 MRI tracers for monitoring immune cell therapy in cancer – FLORIM. Emergence, Université Paris Cité. Coordinator: Claire Mangeney and Florence Gazeau.
2017-2019. As collaborator: NIR-laser-switched smart nanocomposites as contrast agents for photoacoustic imaging and photothermally-activated drug-delivery systems for detection and therapy of peritoneal carcinomatosis – NIRPER, France Life Imaging (FLI) funding. Coordinator: Amanda K. A. Silva and Jérôme Gateau.
Publications
2023
(Review) Y. Zhang, C. Roux, A. Rouchaud, A. Meddahi-Pellé, V. Gueguen, C. Claire, F. Sun*, G. Pavon-Djavid*, Y. Luo*. Recent Advanced in Fe-based bioresorbable stents: materials design and biosafety. Bioac. Mater., 2024, 31, 333-354.
(Article) H. Chen, P. Nizard, S. Nowak, S. Ammar-Merah, Amnon Bar-Shir, Jean Pinson, F. Gazeau*, C. Mangeney*, Y. Luo*, Dual-mode Nanoprobes Based on Lanthanide Doped Fluoride Nanoparticles Functionalized by Aryl Diazonium Salts for Fluorescence and SERS Bioimaging. Small, 2023, 2305346.
(Article) L. Nicchio, J. Médard, P. Decorse, S. Gam-Derouich, A. Chevillot-Biraud, Y. Luo, C. Mangeney, A. Berisha, F. Averseng, M. Fagnoni, S. Protti, J. Pinson*, Selective Nsp2– and Csp2– photografting of Au-Surface by aryldiazonium salts and arylazo sulfonates, Chem. Eur. J, 2023, e202301006.
2022
(Article) Y. Xiao, K. Pandey, A. Nicolas Boluda, D. Onidas, P. Nizard, F. Carn, T. Lucas, J. Gateau, A. Martín-Molina, M. Quesada Pérez, M. del Mar Ramos-Tejada, F. Gazeau*, Y. Luo*, C. Mangeney*, Synergic thermo- and pH-sensitive hybrid microgels loaded with fluorescent dyes and ultrasmall gold nanoparticles for photoacoustic imaging and photothermal therapy, ACS Applied Materials & Interfaces, 2022, 14, 49, 54439–54457.
(Article) D. Li, J. Brunie, F. Sun, P. Nizard, D. Onidas, A. Lamouri, V. Noël, C. Mangeney, G. Mattana*, Y. Luo*, Anti-counterfeiting SERS security labels derived from silver nanoparticles and aryl diazonium salts, Nanoscale Advances, 2022, 4, 5037-5043 (Journal inside cover)
(Article) D. Zhao, Z. Li, X. Yu, W. Zhou, Q. Wu, Y. Luo, N. Wang*, A. Liu*, L. Li*, S. Chen, Ru decorated Co nanoparticles supported by N-doped carbon sheet implements Pt-like hydrogen evolution performance in wide pH range, Chemical Engineering Journal, 2022, 450, 138254.
(Review) D. Li, K. Aubertin, D. Onidas, P. Nizard, N. Félidj, F. Gazeau, C. Mangeney, Y. Luo*. Recent advances in non-plasmonic surface-enhanced Raman spectroscopy nanostructures for biomedical applications. WIREs Nanomedicine and Nanobiotechnology, 2022, 14 (4), e1795.
(Article) D. Li, P. Nizard*, D. Onidas, A. Lamouri, J. Pinson, S. Mahouche-Chergui, K. Aubertin, F. Gazeau, Y. Luo*, C. Mangeney*. SERS tags derived from silver nanoparticles and aryl diazonium salts for cell Raman imaging, Nanoscale, 2022, 14, 1452.
2021
(Review) Y. Xiao, J. Gateau, A. K. A. Silva, X. Shi, F. Gazeau*, C. Mangeney*, Y. Luo*. Hybrid nano-and microgels doped with plasmonic contrast agent for cancer theranostics. View, 2021, 20200176. (Journal cover)
(Review) D. Li, Y. Luo*, D. Onidas, L. He, M. Jing, F. Gazeau, J. Pinson*, C. Mangeney*. Surface fuctionalization of nanomaterials by aryl diazonium salts for biomedial sciences. Adv. Colloid Interface Sci., 2021, 294, 102479.
2020
(Review) I. Kherbouche, Y. Luo, N. Félidj*, C. Mangeney*. Plasmon-Mediated Surface Functionalization: New Horizons for the Control of Surface Chemistry on the Nanoscale. Chem. Mater., 2020, 32, 5442.
(Article) Y. Luo*, Y. Xiao, D. Onidas, L. Iannazzo, M. Ethève-Quelquejeu, A. Lamouri, N. Félidj, S. Mahouche-Chergui, T. Brulé, N. Gagey-Eilstein, F. Gazeau, C. Mangeney*. Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles. Chem. Comm., 2020, 56, 6822.
2018
(Article) S. Gam-Derouich*, J. Pinson, P. Decorse, Y. Luo, R. Herbaut, L. Royon, C. Mangeney*. Diazonium salt chemistry for the design of nano-textured anti-icing surfaces. Chem. Comm., 2018, 54, 8938.
(Article) Y. Li, W. Zhou, J. Dong, Y. Luo, P. An, J. Liu, X. Wu, G. Xu, H. Zhang, J. Zhang. Interface engineered in-situ anchoring Co9S8 nanoparticles into multiple doped carbon matrix: highly efficient zin-air battery. Nanoscale, 2018, 10, 2649.
2017
(Article) Y. Luo, B. Kirchhoff, D. Fantauzzi, L. Cavillo, L.A. Estudillo-Wong, G. Granozzi, T. Jacob, N. Alonso-Vante. Molybdennum-doping augments platinum-copper oxygen reduction electrocatalyst. ChemSusChem, 2017, 10, 1-10.
(Article) H. Zhong+, Y. Luo+, S. He+, P. Tang, D. Li, N. Alonso-Vante, Y. Feng. Electrocatalytic cobalt nanoparticles interacting with nitrogen-doped carbon nanotube in-situ generated from a metal−organic framework for the oxygen reduction reaction. ACS. Appl. Mater. Interfaces, 2017, 9, 2541-2549. (+same contribution)
(Article) K. Miao, Y. Luo, J. Zou, J. Yang, F. Zhang, L. Huang, J. Huang, X. Kang, S. Chen. PdRu alloy nanoparticles of solid solution in atomic scale: outperformance towards formic acid electro-oxidation in acidic medium. Electrochim. Acta, 2017, 251, 588-594.
2016
(Article) Y. Luo, L. Cavillo, C. Daiguebonne, M. K. Daletou, G. Granozzi, N. Alonso-Vante, A Highly Efficient and Stable Oxiygen Reduction Reaction on Pt/CeOx/C Electrocatalyst Obtained via a Sacrificial Precursor Based on a Metal-Organic Framework. Appl. Catal. B, 2016, 89, 39-50.
(Article) Y. Luo, N. Shroti, M. K. Daletou, L. A. Estudillo-Wong, N. Alonso-Vante. Synergistic effect of Yttrium and pyrodine-functionalized carbon nanotube on platinum nanoparticles towards oxygen reduction reaction in acid medium. J. Catal., 2016, 344, 712-721.
(Article) Y. Luo, L. A. Estudillo-Wong, L. Calvillo, G. Granozzi, N. Alonso-Vante. An easy and cheap chemical route using a MOF precursor to prepare Pd-Cu electrocatalyst for efficient energy conversion cathodes. J. Catal., 2016, 338, 135-142.
(Article) Y. Luo, L. A. Estudillo-Wong, N. Alonso-Vante. Carbon Supported Pt-Y2O3 and Pt-Gd2O3 Nanoparticles Prepared via Carbonyl Chemical Route towards Oxygen Reduction Reaction: Kinetics and Stability. Int. J. Hydrogen Energy, 2016, 41, 19601-19609.
(Article) Y. Luo, J. M. Mora-Hernández, N. Alonso-Vante, Morphological impact onto organic fuel oxidation of nanostructured palladium synthesized via carbonyl chemical route, J. Electroanal. Chem., 2016, 765, 79-86.
(Article) L. Timperman+, Y. Luo+, N. Alonso-Vante, On the availability of active sites for hydrogen peroxide and oxygen reduction reaction on highly dispersed platinum nanoparticles, ChemElectroChem, 2016, 3, 1705-1712. (+same contribution)
(Article) S. Freslon, Y. Luo, C. Daiguebonne, G. Calvez, K. Bernot, O. Guillou, Brightness and color tuning in a series of lanthanide-based coordination polymers with benzene-1,2,4,5-tetracarboxylic acid as ligand. Inorg.Chem., 2016, 55, 794.
(Review) M. Mora-Hernández, Y. Luo, N. Alonso-Vante. What can we learn in electrocatalysis, from nanoparticulated precious and/or non-precious catalytic centers interacting with their support? Catalysts, 2016, 6, 145.
(Article) L. A. Estudillo-Wong, Y. Luo, J. A. Diaz-Real, N. Alonso-Vante. Enhanced oxygen reduction reaction stability on platinum nanoparticles photo-deposited onto oxide-carbon composites. Appl. Catal. B, 2016, 187, 291.
2015
(Article) Y. Luo, A. Habrioux, L. Calvillo, G. Granozzi, N. Alonso-Vante, Thermally Induced Strains on the Catalytic Activity and Stability of Pt–M2O3/C (M = Y or Gd) Catalysts towards Oxygen Reduction Reaction, ChemCatChem, 2015, 7, 1573.
(Review) Y. Luo, N. Alonso-Vante, The Effect of Support on Advanced Pt-based Cathodes towards the Oxygen Reduction Reaction. State of the Art. Electrochim. Acta, 2015, 179, 108.
(Article) Y. Luo, J. M. Mora-Hernández, L. A. Estudillo-Wong, E. M. Arce-Estrad, N. Alonso-Vante, Nanostructured palladium tailored via carbonyl chemical route towards oxygen reduction reaction, Electrochim. Acta, 2015, 173, 771.
(Article) E. Torralba-Penalver, Y. Luo, J.-D Compain, S. Chardon-Noblat, B. Fabre, Selective Catalytic Electroreduction of CO2 at Silicon Nanowires (SiNWs) Photocathodes using non-noble metal-based manganese carbonyl bipyridyl molecular catalysts in solution and grafted onto SiNWs, ACS Catal., 2015, 5, 6138.
(Article) J. Ma, A. Habrioux, Y. Luo, G. Ramos-Sanchez, L. Calvillo, G. Granozzi, P. B. Balbuena, N. Alonso-Vante, Electronic Interaction between Platinum Nanoparticles and Nitrogen-doped Reduced Graphene Oxide: Effect on the Oxygen Reduction Reaction, J. Mater. Chem. A, 2015, 3, 11891.